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The Never Ending Story-What Are the Differentiable Magnetic Resonance Imaging Characteristics Between Pyogenic and Mycobacterial Thoracolumbar Infections?
J Clin Med
January 2025
Department of Radiology, Radiotherapy and Nuclear Medicine, National Medical Institute of the Ministry of the Interior and Administration, 02-507 Warsaw, Poland.
: This study aimed to determine if MRI features can distinguish between spinal infections caused by pyogenic bacteria and Mycobacterium tuberculosis. : Patients underwent an MRI of the thoracolumbar spine with and without contrast. Three blinded observers assessed the images, using statistical tests for analysis.
View Article and Find Full Text PDFComparative study of a rabbit model of spinal tuberculosis using different concentrations of .
World J Orthop
January 2025
Department of Orthopedics, The 940 Hospital of Joint Logistic Support Force of Chinese People's Liberation Army, Lanzhou 730000, Gansu Province, China.
Background: Tuberculosis is among the most devastating infectious diseases worldwide. Spinal tuberculosis is not easy to detect at an early stage, which without effective treatment often leads to spinal deformity and spinal cord damage which in turn cause complications such as paraplegia and quadriplegia. In this study, we established a model using three concentrations of bacteria and carried out a comprehensive evaluation of the model by imaging, general observations, and histopathological and bacteriological studies.
View Article and Find Full Text PDFEtiological Insights and the Role of Individual Factors in Infectious Spondylodiscitis.
Infect Dis Rep
January 2025
Department of Physiology, The "Carol Davila" University of Medicine and Pharmacy, 8 Eroii Sanitari Boulevard, 050474 Bucharest, Romania.
Spondylodiscitis can be caused by various microorganisms and has shown a continuous rise in incidence and mortality. The purpose of our study was to analyze the demographic and laboratory data, as well as comorbidities of patients that were surgically treated for spondylodiscitis in our hospital. The causative pathogens involved in the etiology of spinal infections were also assessed.
View Article and Find Full Text PDFspondylitis in a non-tropical immunocompetent patient: a case report and review of the literature.
Front Med (Lausanne)
January 2025
Department of Spine Surgery, Wuhan Fourth Hospital, Wuhan, China.
Background: Tropical Candida spondylitis is an uncommon cause of lower back pain in patients, especially in non-tropical areas or in patients not at risk of immunocompromise.
Case Presentation: A 65-year-old woman presented with a six-month history of poorly managed low back pain, now accompanied by numbness and pain in both lower extremities. Her medical history was significant for tertiary hypertension.
Metagenomic next-generation sequencing for the clinical identification of spinal infection-associated pathogens.
Front Cell Infect Microbiol
January 2025
Department of Spine Surgery, Fuzhou Second General Hospital, Fuzhou, Fujian, China.
Background: This study aimed to evaluate the efficacy of metagenomic next-generation sequencing (mNGS) technology for identifying pathogens associated with spinal infection (SI).
Methods: A retrospective analysis was conducted on clinical data from 193 patients with suspected SI between August 2020 and September 2024. Based on histopathological results, the patients were divided into the SI group (n=162) and the non-SI group (n=31).
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