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BMC Infect Dis
December 2024
Department of Infectious Diseases, the Third People's Hospital of Chengdu, Chengdu, Sichuan, 610031, China.
To enhance the current clinical understanding and improve the diagnosis and treatment of Actinotignum schaalii infections, we have presented here a report of the case of recurrent infections at a periumbilical scar, induced by Actinotignum schaalii and complicated by abscess formation in a 50-year-old woman with persistent festering at the site of a periumbilical scar after laparoscopy 9 years ago, with subsequent ruptures over the past 2 years. Physical examination revealed a radial fold scar with localized redness and slight swelling of the skin below the navel. Although no significant increase in the local skin temperature was noted, tenderness was present.
View Article and Find Full Text PDFCureus
September 2024
Urology, Orlando Regional Medical Center, Orlando, USA.
Ejaculatory dysfunction in adult males with bladder exstrophy-epispadias complex can occur from associated genitourinary anomalies, surgical iatrogenic scarring, infection, obstruction, and neurologic and functional causes. This case presents a 30-year-old male patient with a history of bladder exstrophy reconstruction (bladder neck closure and appendicovesicostomy) who presented with a nine-year history of intermittent perineal scrotal pain, swelling, and intermittent urethral discharge. He presented with a tender palpable perineal mass ("semen-oma").
View Article and Find Full Text PDFLipids Health Dis
October 2024
Heart and Lung Center, Cardiology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.
The risk of atherosclerotic cardiovascular diseases (ASCVDs) can be reduced by lowering low-density lipoprotein cholesterol (LDL-C) concentrations. Nevertheless, ASCVDs still cause most deaths worldwide. Here, we discuss the prevention of ASCVD and the event risk with a focus on heart-healthy diets, i.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
October 2024
Applied Zoology and Nature Conservation, Zoological Institute and Museum, University of Greifswald, Greifswald 17489, Germany.
Hibernation is a widespread and highly efficient mechanism to save energy in mammals. However, one major challenge of hibernation is maintaining blood circulation at low body temperatures, which strongly depends on the viscoelastic properties of red blood cells (RBCs). Here, we examined at physiologically relevant timescales the thermomechanical properties of hundreds of thousands of individual RBCs from the hibernating common noctule bat (), the nonhibernating Egyptian fruit bat (), and humans ().
View Article and Find Full Text PDFAdv Mater
November 2024
Nanotheranostics Laboratory, Division of Innovative Diagnostic and Therapeutic Research, Institute of Photonics Medicine, Hamamatsu University School of Medicine, 1-20-1, Handayama, Chuo-ku, Hamamatsu, 431-3192, Japan.
Tumor microscopic structure is crucial for determining properties such as cancer type, disease state (key for early diagnosis), and novel therapeutic strategies. Magnetic particle imaging is an early cancer diagnostic tool using magnetic nanoparticles as a tracer, which actualizes cancer theranostics in combination with hyperthermia treatment using the abilities of magnetic nanoparticles as a heat source. This study focuses on the microscopic structures associated with cancer cell distribution, the stromal compartment, and vascularization in different kinds of living tumors by analyzing the intratumor magnetic relaxation response of magnetic nanoparticles injected into the tumors.
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