Five hundred girls with recurrent urinary tract infections and documented reflux were seen in our private practice during the last twenty years. All patients received medical treatment for three to forty-eight months (an average of fifteen months) after which the 250 who were not cured were submitted to corrective surgery. The primary reason for antireflux surgery is to protect the kidney from the damaging effect of a combination of high pressure and infection. Thus our criteria for operation included persistent infection, renal changes typical of past pyelonephritis, major reflux, and abdominal or flank pain. Our surgical cure rate after careful long-term follow-up is 96%. Our medical-surgical cure rate at the end of two years reached 88%. This experience has enabled us to evolve a rigorous point system providing common denominators regardind indications for operation. It emphasizes the desirability of attempting a medical cure for at least one year after urethral dilatation, except where major orifice defects and major reflux exist. This system should help to increase communication and coordination of efforts between pediatrician, radiologist, and urologist.
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http://dx.doi.org/10.1016/0090-4295(80)90329-5 | DOI Listing |
Langmuir
January 2025
Department of Chemistry, Indian Institute of Technology Patna, Patna 801103, Bihar, India.
Polyoxometalates (POMs) are composed of nanometric metal-oxide anions and have rich solution chemistry. In this class, Keggin POMs have been identified as the most influential inorganic additives for aqueous nonionic soft matter systems. POMs being at the borderline of classical ions and charged colloids possess fascinating solution properties; the present work aims to delve deeper into the interactions between nanoions and nonionic soft matters from a spectroscopic point of view.
View Article and Find Full Text PDFEur Thyroid J
January 2025
F Langhauser, Neurology, University Hospital Essen Department of Neurology, Essen, Germany.
Objective Thyroid hormones (TH) control a variety of processes in the central nervous system and influence its response to different stimuli, such as ischemic stroke. Post-stroke administration of 3,3',5-triiodo-L-thyronine (T3) has been reported to substantially improve outcomes, but the optimal dosage and time window remain elusive. Methods Stroke was induced in mice by transient middle cerebral artery occlusion (tMCAO) and T3 was administered at different doses and time points before and after stroke.
View Article and Find Full Text PDFPLoS One
January 2025
Faculdade de Ciências Médicas, Universidade Estadual de Campinas (UNICAMP), Campinas, São Paulo, Brazil.
Background And Objective: One of the functions attributed to the auditory efferent system is related to the processing of acoustic stimuli in noise backgrounds. However, clinical implications and the neurophysiological mechanisms of this system are not yet understood, especially on higher regions of the central nervous system. Only a few researchers studied the effects of noise on cortical auditory evoked potentials (CAEP), but the lack of studies in this area and the contradictory results, especially in children, point to the need to investigate different protocols and parameters that could allow the study of top-down activity in humans.
View Article and Find Full Text PDFAnn Med
December 2025
Department of Radiology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Background: Calcinosis cutis of hands can progress and impair hand function in systemic sclerosis (SSc). Understanding the natural disease and comprehensive management is crucial.
Objective: To examine clinical course and identify risk factors associated with progressive calcinosis cutis in early SSc.
Mil Med
January 2025
Department of the Air Force Exercise Science Unit, JBSA-Randolph, TX 78150, USA.
Introduction: Physical fitness is an integral part of military readiness, and failure to meet military Physical Fitness Assessment (PFA) standards can severely damage or end careers. Postpartum active duty service members experience a drop in PFA scores and passing rates compared to their pre-pregnancy assessments. Each branch recently extended recovery time to 12 months, but more research is required to see if this change alone is enough to return both active duty and reserve component postpartum personnel to their own preconception PFA outcomes (scores, passing rates, and injury rates) and those of a control group of nullpartum female airmen.
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