21 patients with soft tissue sarcomas were treated after surgery with adriamycin alone or in combination with other drugs. 13 patients had additional local radiotherapy. 12 of thde 21 patients received chemotherapy as an adjuvant to surgery. 19 patients concurrently receiving palliative treatment for advanced soft tissue sarcoma in the form of adriamycin and adriamycin combinations served as controls. Results collected to date point to an improvement in the prognosis of soft tissue sarcomas, when radical surgery is followed by intensive subsequent cytostatic treatment. However, the present results await confirmation from prospective randomized studies now taking place. Some of the side effects of this treatment were very pronounced and led to the premature interruption of the trial in 24% of cases.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Application of mean maximum Young's modulus value as a new parameter for differential diagnosis of prostate diseases.
Sci Rep
January 2025
Jun Shi Department of Ultrasound, The First Hospital of Hebei Medical University, Shijiazhuang City, 050031, Hebei Province, China.
Transrectal shear wave elastography (T-SWE) can be used non-invasively to diagnose prostate cancer (PCa) and benign prostatic hyperplasia (BPH). The prostate tissue can be viewed as an ellipsoidal sphere with viscoelastic characterization. Linear elastic model has been used to characterize soft tissues, and the simplification of partial characterization provides incomplete information.
View Article and Find Full Text PDFEngineered hydrogel biomaterials facilitate lung progenitor cell differentiation from induced pluripotent stem cells.
Am J Physiol Lung Cell Mol Physiol
January 2025
Department of Bioengineering, University of Colorado, Denver | Anschutz Medical Campus, Aurora, CO, USA.
Lung progenitor (LP) cells identified by the expression of transcription factor NK2 homeobox 1 (NKX2.1) are essential for development of all lung epithelial cell types and hold tremendous potential for pulmonary research and translational regenerative medicine applications. Here we present engineered hydrogels as a promising alternative to the naturally derived materials that are often used to differentiate human induced pluripotent stem cells (iPSCs) into LP cells.
View Article and Find Full Text PDFVolumetric assessment of the soft tissue envelope in unilateral closed ankle fractures using a portable 3D scanner.
J Foot Ankle Surg
January 2025
Department of Orthopedic and Trauma Surgery, University Hospital Düsseldorf Moorenstraße 5, 40255 Düsseldorf, Germany. Electronic address:
Management of ankle fractures necessitating surgery is impacted by soft tissue swelling, often delaying open reduction and internal fixation (ORIF). Subjective evaluations are inconsistent, and traditional measurement methods are often inaccurate or impractical. This prospective observational study included 17 adults with unilateral closed ankle fractures requiring surgical fixation.
View Article and Find Full Text PDFThe role of ultrasound in facial hyaluronic acid dermal filler injections - A review article.
Clin Imaging
January 2025
Department of Radiological Sciences, Ultrasound Program, Princess Nourah Bint Abdulrahman University. Electronic address:
Injectable dermal fillers have seen a remarkable rise in popularity in recent years for aesthetic enhancements, such as facial contouring and rejuvenation. Hyaluronic acid (HA)-based fillers are especially favored due to their tolerability, minimal invasiveness, and effectiveness. This review examines the applications of ultrasound in HA dermal filler procedures.
View Article and Find Full Text PDFPaediatric traumatic brain injuries: A descriptive analysis of incidence, visits, cause, and admission rates in Iceland from 2010 to 2021.
Int Emerg Nurs
January 2025
Department of Physical Therapy, Faculty of Medicine, School of Health Sciences, University of Iceland, and Research Institute of Neurobehavioral Rehabilitation, Landspitali University Hospital, Iceland.
Background: Traumatic brain injuries (TBI) are common in emergency departments (ED) and may cause long-term negative outcomes but knowledge on how the first assessment of children with TBI may predict outcomes is lacking. This study aimed to expand the knowledge by describing the incidence, visits, causes, and outcomes of TBI in children in Iceland.
Methods: A retrospective descriptive data analysis was conducted on electronic medical records of children aged 0-17 that visited Landspitali EDs due to a traumatic head injury in 2010-2021.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!