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In order to evaluate the intestinal absorption of calcium in end-stage renal disease, whole-body 47Ca retention was determined using a whole-body counter in 18 patients undergoing chronic hemodialysis and in 12 normal volunteers. The results of the above study were compared with those obtained by measuring plasma radioactivity after oral load of 47Ca. A significantly lower whole-body retention of 47Ca was found in hemodialysis patients, as compared with normal subjects, and the results were similar to those of the direct calcium-absorption test. These findings suggest that whole-body 47Ca retention can be used as an index of intestinal calcium absorption in patients with chronic renal failure.
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