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Atrial fibrillation burden in clinical practice, research, and technology development: a clinical consensus statement of the European Society of Cardiology Council on Stroke and the European Heart Rhythm Association.
Europace
March 2025
Clinical Cardiac Academic Group, Genetic and Cardiovascular Sciences Institute, City-St George's University of London, London, UK.
Atrial fibrillation (AF) is one of the most common cardiac diseases and a complicating comorbidity for multiple associated diseases. Many clinical decisions regarding AF are currently based on the binary recognition of AF being present or absent with the categorical appraisal of AF as continued or intermittent. Assessment of AF in clinical trials is largely limited to the time to (first) detection of an AF episode.
View Article and Find Full Text PDFResearch progress of cycloartane triterpenoids and pharmacological activities.
Arch Pharm (Weinheim)
March 2025
School of Pharmaceutical Sciences & Institute of Materia Medica, Shandong First Medical University & Shandong Academy of Medical Sciences, NHC Key Laboratory of Biotechnology Drugs (Shandong Academy of Medical Sciences), Key Laboratory for Rare & Uncommon Diseases of Shandong Province, Jinan, China.
Cycloartane triterpenoids are widely distributed in the plant kingdom, and there have been reports of hundreds of families containing cycloartane triterpenoids. But the types and content of cycloartane are different among various plants. In recent years, a large amount of cycloartane triterpenoids have been extracted and studied from different plants, and some types of cycloartane triterpenoids exhibit great pharmacological activities in terms of antiaging, antioxidant, anti-inflammatory, anticancer, antiarrhythmic effects, and so on.
View Article and Find Full Text PDFDaily Heart Rate Variability in Dogs With Atrial Fibrillation.
J Vet Intern Med
March 2025
Department of Clinical Studies and Advanced Medicine, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Background: Daily variability of heart rate in 24-h Holter recordings in dogs with atrial fibrillation (AF) receiving antiarrhythmic drugs (AAD) is unknown and could influence medical decisions.
Hypothesis/objectives: Dogs with AF, Holter-derived mean heart rate (meanHRHolter) over 24 h is not significantly different from a subsequent, consecutive 24-h period.
Animals: Twenty-five dogs with AF.
Efficacy and safety of adenosine for supraventricular tachycardia: A meta-analysis utilizing BioMedGPT-LM-7B.
BMC Cardiovasc Disord
March 2025
School of International Pharmaceutical Busines, China Pharmaceutical University, #639 Longmian Dadao, Jiangning District, Nanjing, 211198, China.
Background: Patients with supraventricular tachycardia (SVT) often experience multiple clinical symptoms that require emergency treatment. This study utilized BioMedGPT-LM-7B, an artificial intelligence (AI) model, to comprehensively evaluate the efficacy and adverse effects of adenosine/adenosine triphosphate (ATP) versus calcium channel blockers (CCBs) in SVT treatment.
Methods: This study conducted a comprehensive search of multiple medical databases, as well as major trial registries up to December 2024.
Rare Allergic Reaction to Local Anesthesia: A Case Report.
Iran J Allergy Asthma Immunol
February 2025
Department of Preventive Dentistry, College of Dentistry, Jouf University, Sakaka, Kingdom of Saudi Arabia.
One of the most commonly used local anesthetic (LA) agents in dentistry is lidocaine. Hypersensitivity reactions to lidocaine have been reported. In such cases, it is crucial to record a detailed clinical history and perform allergy testing to select a suitable alternative LA agent.
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