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Addition of continuous glucose monitoring to glucagon-like peptide 1 receptor agonist treatment for type 2 diabetes mellitus - An economic evaluation.
J Manag Care Spec Pharm
January 2025
Abbott Diabetes Care, Mississauga, Ontario, Canada.
Background: Both glucagon-like peptide 1 receptor agonists (GLP-1 RAs) and continuous glucose monitoring (CGM) have been shown to improve glycated hemoglobin A1c (A1c) levels among patients with type 2 diabetes mellitus (T2DM). Recently, a US real-world study found statistically significant improvements in A1c levels among patients using GLP-1 RA and a CGM device, compared with a matched cohort receiving only GLP-1 RA.
Objectives: To assess the cost-effectiveness from a US payer perspective of initiating CGM (FreeStyle Libre Systems) in people living with T2DM using a GLP-1 RA therapy, compared with GLP-1 RA alone.
Efficacy of three predictive models for deep vein thrombosis in patients with lumbar disc herniation.
Am J Transl Res
December 2024
Department of Traditional Chinese Medicine, The First Hospital of Hebei Medical University Shijiazhuang 050091, Hebei, China.
Objective: To develop predictive models for assessing deep vein thrombosis (DVT) risk among lumbar disc herniation (LDH) patients and evaluate their performances.
Methods: A retrospective study was conducted on 798 LDH patients treated at the First Hospital of Hebei Medical University from January 2017 to December 2023. The patients were divided into a training set (n = 558) and a test set (n = 240) using computer-generated random numbers in a ratio of 7:3.
Effects of Supplementation With Different Specificities of Dietary Fiber on Health-Related Indicators in Adults With Overweight or Obesity: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
Nutr Rev
January 2025
Sports Nutrition Center, National Institute of Sports Medicine, Beijing 100029, China.
Context: Dietary fiber (DF) exhibits variations in its chemical and physical complexity, as well as in its utilization by the gut microbiota. However, the impact of these differences on the health status of adults with overweight or obesity remains unclear.
Objective: This meta-analysis aimed to explore the varying effects of supplementing with different specificities of DF on the health of adults with overweight or obesity, providing guidance on selecting DF supplementation to improve health status.
Effectiveness and Safety of Vildagliptin Sustained Release in the Management of Type 2 Diabetes Mellitus: Real-World Evidence in Indian Patients [NOVELTY Study].
Drugs Real World Outcomes
January 2025
Department of Medical Affairs, Cipla Ltd., Mumbai Central, Mumbai, Maharashtra, 400008, India.
Background And Objective: Vildagliptin sustained release (XR), a formulation that provides vildagliptin 100 mg with a once-daily dose administration, is a recent introduction to manage type 2 diabetes mellitus in India. This study aimed to evaluate the effectiveness and tolerability of vildagliptin XR in patients with type 2 diabetes in real-world clinical settings.
Methods: This was an observational, prospective, multicenter, cohort study conducted in India, which included patients with type 2 diabetes uncontrolled on metformin XR monotherapy with glycated hemoglobin (HbA1c) > 7.
Child sleep problems mediate prospective associations between fathers' parenting stress and child blood glucose levels.
J Fam Psychol
January 2025
Department of Biobehavioral Health, Pennsylvania State University.
The present study examined the role of first-time fathers' parenting stress during infancy in relation to children's mean blood glucose via glycated hemoglobin (HbA1c) levels during middle childhood while also exploring the mediating role of child sleep problems in this association. A total of 306 fathers self-reported on parenting stress when their children were 10 months old (49% of girls). Fathers also reported on child sleep problems when their children were 24 months old.
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