Prior studies on twin biparietal growth have resulted in conflicting conclusions. This study was designed to establish definitive criteria based on both ultrasonic biparietal diameter (BPD) and newborn anthropometric data for normal versus abnormal growth in multiple pregnancies. Fetal BPD and newborn head circumference values among concordant twins were similar to those of appropriate for gestational age (AGA) singletons at all gestational ages. Singleton standards can therefore be applied to evaluate the adequacy of twin BPD growth even in the third trimester. Ultrasonic criteria for the diagnosis of discordancy include an intrapair difference in BPD of 5 mm or more and an intrapair difference greater than 5% in ultrasonically measured fetal head circumferences. Discordant BPD growth noted prior to the third trimester suggests twin-transfusion syndrome and is associated with a high perinatal mortality. In contrast, divergent BPD growth beginning after 30 weeks' gestation appears to have a better prognosis.
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Biomedicines
December 2024
Department of Neonatology, Osaka Women's and Children's Hospital, Izumi 594-1101, Japan.
Background: It has been demonstrated that aspiration during endotracheal intubation in preterm infants with gastroesophageal reflux is a contributing factor in the worsening of lung diseases and the development of bronchopulmonary dysplasia (BPD). This study aims to compare the safety and efficacy of early transpyloric (TP) tube feeding with that of nasogastric (NG) tube feeding in relation to BPD.
Methods: The study population consisted of 39 extremely low birth weight infants (ELBWIs) with mechanical ventilation and an enteral feeding volume of 50 mL/kg/day, which were randomly assigned to different groups based on the method of tube feeding.
Sci Total Environ
December 2024
Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, 81 Meishan Road, Hefei 230032, China; MOE Key Laboratory of Population Health Across Life Cycle, 81 Meishan Road, Hefei 230032, Anhui, China. Electronic address:
Obes Surg
January 2025
Department of Surgery, Mayo Clinic, Rochester, MN, 55905, USA.
Purpose: The effectiveness of biliopancreatic diversion with duodenal switch (BPD/DS) for weight loss is well established, yet there remains ongoing debate over optimal limb lengths to maximize weight loss without compromising safety. We aimed to evaluate the impact of BPD/DS limb lengths on weight loss outcomes and comorbidity resolution.
Material And Methods: A multicenter review of patients who underwent primary BPD/DS between 2008 and 2022.
Am J Physiol Lung Cell Mol Physiol
December 2024
Department of Pediatrics, Boston Medical Center, Boston University Chobanian and Avedisian School of Medicine, Boston, MA.
Intrauterine inflammation from chorioamnionitis (CA) is associated with placental dysfunction and increased risk of bronchopulmonary dysplasia (BPD), the chronic lung disease of prematurity. Antenatal steroid (ANS) treatment improves early respiratory outcomes for premature infants. However, it remains unclear whether ANS improve long-term respiratory outcomes, and whether these effects are mediated through improvement of placental dysfunction and/or direct impact on the fetal lung.
View Article and Find Full Text PDFInt Arch Allergy Immunol
December 2024
Objective: Epithelial-mesenchymal transition (EMT) of alveolar epithelial cells is an important mechanism for the onset and development of broncho-pulmonary dysplasia (BPD).The role of FGF-2 in BPD is currently unclear. The aim of our study is to investigate the expression of FGF-2 in lung tissue of BPD mice, to further clarify the effect of FGF-2 on EMT in alveolar epithelial cells and to actively search for possible signaling pathways.
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