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Functional genomic insights into Floricoccus penangensis ML061-4 isolated from leaf surface of Assam tea.
Sci Rep
January 2025
School of Microbiology, University College Cork, Cork, T12 YT20, Ireland.
Floricoccus penangensis ML061-4 was originally isolated from the leaf surface of an Assam tea plant (Camellia sinensis var. assamica) from Northern Thailand. To assess the functions encoded by the F.
View Article and Find Full Text PDFNeurochemical Alterations Linked to Persistent COVID-19-Induced Anosmia: Probing Into Orbitofrontal Cortex by Magnetic Resonance Spectroscopy.
Acad Radiol
January 2025
Department of Otolaryngology and Head and Neck Surgery, School of Medicine, Otorhinolaryngology Research Center, Guilan University of Medical Sciences, Rasht, Iran (M.H.D., S.N.). Electronic address:
Background: While many COVID-19-induced anosmia patients recover their sense of smell within a few months, a substantial number of them continue to experience olfactory impairment. In our primary study, the metabolic patterns in orbitofrontal cortex (OFC) were observed to exhibit more alterations than other regions. Hence, this study specifically probes into alterations within OFC region in subjects with persistent COVID-19-induced anosmia.
View Article and Find Full Text PDFAculeanoids A-D, the second 17-nor fusicoccane diterpenoids with immunosuppressive activity from Aspergillus aculeatus.
Phytochemistry
January 2025
Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, PR China. Electronic address:
Chemical investigation on the secondary metabolites of Aspergillus aculeatus led to the identification of ten modified fusicoccane-type diterpenoids aculeanoids A-J (1-10). Their structures and absolute configurations were characterized by comprehensive spectroscopic analysis, DP4+ analysis, Mo(OAc)-induced ECD, single-crystal X-ray diffractions, and ECD calculations. Compounds 1-4 belong to a rare class of 17-nor fusicoccane diterpenoids, with only one previously reported example.
View Article and Find Full Text PDFIron limitation triggers roseoceramide biosynthesis and membrane remodeling in marine roseobacter.
Proc Natl Acad Sci U S A
January 2025
Department of Chemistry, Princeton University, Princeton, NJ 08544.
Chemical communication between marine bacteria and their algal hosts drives population dynamics and ultimately determines the fate of major biogeochemical cycles in the ocean. To gain deeper insights into this small molecule exchange, we screened niche-specific metabolites as potential modulators of the secondary metabolome of the roseobacter, . Metabolomic analysis led to the identification of a group of cryptic lipids that we have termed roseoceramides.
View Article and Find Full Text PDFCombining resistance indicators, metabolomes and transcriptomes to reveal correlations in disease and cold resistance in tea plant and analyze the key domain NB-ARC.
Plant Cell Rep
January 2025
Department of Tea Science, College of Horticulture Science, South China Agricultural University, Guangzhou, 510642, China.
Integration of resistance indicators, metabolomes, and transcriptomes to elucidate that there is a positive correlation between disease susceptibility and cold tolerance in tea plants. The flavonoid pathway was found to be the major metabolic and transcriptional enrichment pathway. A key domain NB-ARC was identified through joint analysis, along with analysis of key domains within the NB-ARC protein.
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