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Castleman's Disease Presenting as an Unusual Pelvic Retroperitoneal Mass.
Cureus
October 2024
General Surgery, Shri B. M. Patil Medical College Hospital and Research Centre, BLDE (Deemed to be University), Vijayapura, IND.
Castleman's disease (CD) is characterised by benign lymphoepithelial proliferation and is a peculiar form of angiofollicular lymph node hyperplasia rather than a neoplasm or a hamartoma. CD is broadly classified as unicentric CD (UCD) and multicentric CD. In the unicentric variant, patients have localised disease affecting only a single lymph node or a group of adjacent nodes in a single region, which clinically presents as an enlarging mass without any other significant symptoms.
View Article and Find Full Text PDFRetroperitoneal paraduodenal unicentric Castleman disease: case report and review of the literature.
J Surg Case Rep
February 2024
Department of Biomedical Science, Hematologic Unit, University of Catania, Policlinico "G. Rodolico-San Marco", Via S. Sofia 78, 95123 Catania, Italy.
Castleman disease is a rare and benign disorder, characterized by enlarged lymph nodes and angiofollicular lymphoid hyperplasia. We report a case of a 57-year-old male, who was admitted to our surgical department because of a retroperitoneal nodular mass measuring about 4 cm in maximum diameter, incidentally discovered on a radiologic exam performed for the onset of vague abdominal pain with posterior irradiation. The patient was subdue to laparoscopic removal of the mass and no intra- and post-operative complications were recorded.
View Article and Find Full Text PDFRetroperitoneal Castleman's disease in a young Nepalese girl: A rare cause of childhood abdominal mass.
Ann Med Surg (Lond)
February 2024
Pathology.
Introduction: Castleman's disease (CD), or benign angio-follicular lymph node hyperplasia, is an uncommon condition in childhood. When a child presents with a huge retroperitoneal mass and inconclusive findings on clinico-radiological evaluation or tissue sampling, management becomes exceedingly difficult. CD herein becomes an uncommon presentation of an uncommon diagnosis.
View Article and Find Full Text PDFCastleman's Disease and Anticonvulsant Therapy: A Case of 52-Year-Old Female.
Cureus
December 2021
Internal Medicine, King Fahad University Hospital, Al Khobar, SAU.
Castleman's disease is a disorder of the lymph nodes that encompasses heterogeneous clinical conditions and can be classified into two main types - hyaline vascular and plasma cell. The affected age group ranges widely from two to 80 years old at the time of diagnosis, with a variable clinical presentation. The etiology of Castleman's disease is not yet well-understood; however, a number of factors have been linked to its pathogenesis including certain cytokines, viral infections, autoimmunity, immunodeficiency, chronic inflammation, and Kaposi sarcoma.
View Article and Find Full Text PDFUnusual Presentation of Castleman's Disease Encroaching on the Brachial Plexus.
Cureus
August 2021
Department of Medical and Population Health Sciences Research, Florida International University Herbert Wertheim College of Medicine, Miami, USA.
Castleman's disease is an uncommon benign lymphoproliferative disorder that commonly involves the mediastinum. We report an unusual case that involves the presentation of unicentric Castleman's disease in a 52-year-old female. The patient had a supraclavicular mass extending onto the brachial plexus.
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