In almost half (46.5%) of 400 chemico-toxicological investigations suspected poisoning had been assumed without a specific poison being named. In 73% of these cases toxicologically important substances were demonstrated. In 19% of cases no poison could be demonstrated and in approximately 6% of cases poison ingestion could neither be ascertained nor ruled out. In 53.5% of emergency investigations suspected poisons could be named before the beginning of analysis. The information could be verified partially or completely in 78%. In 20% of these more poisonous substances were found than suspected and in 16.3% none of the suspected substances but completely different toxic ones were demonstrable. In 5.6% of cases suspected poison ingestion could not be verified.
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http://dx.doi.org/10.1055/s-2008-1070746 | DOI Listing |
J Ovarian Res
January 2025
Department of Health Education, Nanjing Municipal Center for Disease Control and Prevention, No.3, Zizhulin Road, Nanjing, Jiangsu Province, 210003, China.
Background: PARP inhibitors (PARPis) have shown promising effectiveness for ovarian cancer. This network meta-analysis (PROSPERO registration number CRD42024503390) comprehensively evaluated the effectiveness and safety of PARPis in platinum-sensitive recurrent ovarian cancer (PSROC).
Methods: Articles published before January 6, 2024 were obtained from electronic databases.
Genome Med
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Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ, USA.
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View Article and Find Full Text PDFScand J Trauma Resusc Emerg Med
January 2025
Health Services Management Research Center, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran.
Background: One way to measure emergency department (ED) performance is using key performance indicators (KPIs). Thus, identifying reliable KPIs can be critical in appraising ED performance. This study aims to introduce and classify the KPIs related to ED in simulations through the Balanced Scorecard (BSC) framework.
View Article and Find Full Text PDFJ Transl Med
January 2025
Department of Radiation Oncology, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, 510060, People's Republic of China.
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View Article and Find Full Text PDFCell Commun Signal
January 2025
Institute of Cancer Stem Cell, Dalian Medical University, Dalian, Liaoning Province, China.
Background: Intracellular membraneless organelles formed by liquid-liquid phase separation (LLPS) function in diverse physiological processes and have been linked to tumor-promoting properties. The nucleolus is one of the largest membraneless organelle formed through LLPS. Deubiquitylating enzymes (DUBs) emerge as novel therapeutic targets against human cancers.
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