One hundred thirty-four cases of Stages III and IV nodular non-Hodgkin's lymphoma, subclassified according to the criteria of Rappaport, were assessed for parafollicular small lymphocytes and vascular prominence and degree of nodularity. Statistically significant correlations with survival were found for the groups in the Rappaport classification but not for groups based on the amount of parafollicular small lymphocytes or vascular prominence (PSL grading). In the subgroup of patients with nodular poorly differentiated lymphocytic lymphoma, a significant difference in survival time was found between those with pure nodular patterns and those with 25--60% diffuse areas.
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http://dx.doi.org/10.1002/1097-0142(19800501)45:9<2364::aid-cncr2820450921>3.0.co;2-q | DOI Listing |
Clin Endocrinol (Oxf)
May 2024
Coordinator of the International Head and Neck Scientific Group, Padua, Italy.
Introduction: Medullary thyroid carcinoma (MTC) is a rare neuroendocrine tumor from parafollicular cells that produce calcitonin (Ct). Despite several existing guidelines for the surgical management of sporadic MTC (sMTC), optimal initial surgical management of the thyroid, the central and the lateral neck remains a matter of debate.
Methods: A systematic review in PubMed and Scopus for current guidelines addressing the surgical management of sMTC and its referenced citations was conducted as per the PRISMA guidelines.
Microsc Microanal
April 2024
Department of Cytology and Histology, Faculty of Veterinary Medicine, Mansoura University, Mansoura 35516, Egypt.
The microstructure of the thyroid gland of the one-humped camel (Camelus dromedarius) was described using morphometric, histological, immunohistochemical staining, and ultrastructural standard techniques. The follicular secretory units of the thyroid glands displayed comparable and variable sizes where the large follicles were situated at the peripheral margins; however, the small ones were located in the central region. Semisquamous epithelium (low cuboidal) lined the large thyroid follicles, while high cuboidal (columnar) epithelium lined the small ones.
View Article and Find Full Text PDFOncol Lett
October 2023
Department of Pathology, Weifang People's Hospital, Weifang, Shandong 261041, P.R. China.
Papillary thyroid cancer (PTC) and medullary thyroid cancer (MTC) originate from follicular and neuroendocrine parafollicular C cells, respectively. PTC and MTC simultaneously exist in tumors containing both MTC and PTC features in a rare condition known as mixed medullary-follicular thyroid carcinoma (MMFTC). In the present study, a 60-year-old female presented with a small mass on the left side of the neck.
View Article and Find Full Text PDFUltrastruct Pathol
February 2023
Medical Histology and Cell Biology Department, Mansoura Faculty of Medicine, Mansoura, Egypt.
Potassium dichromate is widely used in various laboratory and industrial applications. Vitamin C and melatonin are well-known antioxidants. Study the microscopic and morphometric alterations in the thyroid gland in adult male albino rats after the administration of potassium dichromate for successive 2 months and also to assess the possible protective effect of vitamin C versus melatonin on these changes.
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