A child with Beckwith-Wiedemann syndrome is described. Growth hormone levels were normal, but circulating somatomedin activity was increased. The role of somatomedins in this condition, and the possibility of a feedback mechanism controlling somatomedin production are discussed.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1626669PMC
http://dx.doi.org/10.1136/adc.55.2.151DOI Listing

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