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Changes in vaginal gene expression and anogenital distance during gilt reproductive development.
Anim Reprod
December 2024
Department of Animal Science, South Dakota State University, Brookings, SD, U.S.A.
Early puberty is associated with improved long-term reproductive performance. Predicting who will achieve early puberty is limited to intensive, invasive serial blood collections for measurement of reproductive hormones. The vaginal genome during pubertal development has potential as biomarkers of early estrus in the pre-pubertal period.
View Article and Find Full Text PDFAssociation between heavy metal exposure and bacterial vaginosis: A cross-sectional study.
PLoS One
January 2025
Department of Clinical Laboratory Medicine, Guangdong Provincial Key Laboratory of Major Obstetric Diseases, Guangdong Provincial Clinical Research Center for Obstetrics and Gynecology, The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Bacterial vaginosis (BV) is a prevalent cause of vaginal symptoms in women of reproductive age. With the widespread of heavy metal pollutants and their harmful function on women's immune and hormonal systems, it is necessary to explore the association between heavy metal exposure and BV. This study investigates the potential relationship between serum heavy metals and bacterial vaginosis in a cohort of American women.
View Article and Find Full Text PDFEffects of epidural esketamine versus sufentanil on labor analgesia and postpartum depression: a retrospective cohort study.
BMC Anesthesiol
January 2025
Department of Anesthesiology, The Third Affiliated Hospital of Zhengzhou University, No. 7, Zhengzhou Kangfufront Street, Zhengzhou, Henan, 450052, China.
Objective: There is a lack of research on epidural esketamine for labor analgesia. The purpose of this research is to compare the efficacy of epidural esketamine and sufentanil on labor analgesia and postpartum depression.
Methods: A total of 187 cephalic full-term parturients with single-fetus vaginal delivery were collected in this retrospective study from Jan 2022 to Jan 2023.
Detection and Molecular Diversity of in Pastoral Livestock in North-Eastern Ethiopia.
Pathogens
December 2024
Institute of Biotechnology, Addis Ababa University, Addis Ababa P.O. Box 1176, Ethiopia.
Brucellosis is a neglected zoonotic disease affecting livestock and humans that remains endemic in Ethiopia. Despite its prevalence, only a few studies have identified species circulating in livestock in the country. This study aimed to determine the species responsible for infections in livestock in the Afar region of Ethiopia and characterize the isolates using whole-genome single nucleotide polymorphism (wgSNP) analysis and in silico multi-locus sequence typing (MLST).
View Article and Find Full Text PDFNovel Isoxazole-Based Antifungal Drug Candidates.
Int J Mol Sci
December 2024
Department of Organic Chemistry and Drug Technology, Faculty of Pharmacy, Wroclaw Medical University, 50-556 Wroclaw, Poland.
Microbiological communities have a significant impact on health and disease. are ubiquitous fungal pathogens that colonize the mucosal surfaces of the genital, urinary, respiratory, and gastrointestinal tracts, as well as the oral cavity. If the immune system is inadequate, then infections may pose a significant threat.
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