It has been suggested that hemodialysis patients might benefit from zinc supplements. However, little attention is given to the trace element content of renal dialysis fluids or to contamination of such fluids with trace metals. Pre- and postdialysis plasma copper and zinc concentrations of patients at two hospital dialysis units were measured by atomic absorption spectrophotometry. The plasma zinc concentration increased substantially in 34 of 37 patients as a result of dialysis. Measurement of dialysate zinc concentrations after primary source of zinc. Because of the possibility of zinc toxicity, zinc nutritional status should be carefully evaluated before recommending zinc supplementation for dialysis patients. Uremic patients dialyzed with certain disposable Cuprophan-membrane coils receive substantial quantities of zinc during dialysis; other Cuprophan-membrane coils tested released negligible quantities of zinc.
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