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Cantharidin (1%), podophyllin (5%), and salicylic acid (30%) formulation in recalcitrant plantar warts: Analysis of 48 patients.
J Med Virol
September 2024
Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), University Podiatric Clinic, Complutense University of Madrid, Madrid, Spain.
A plantar wart is a benign hyperplasia that appears on the feet due to the human papillomavirus (HPV). One method used for the treatment of recalcitrant plantar warts, those lasting over 2 years or persisting after at least two treatment attempts, is the cantharidin (1%), podophyllin (5%), and salicylic acid (30%) formulation, also known as the CPS formulation. Although this method is in use, there are few studies on it.
View Article and Find Full Text PDFSuccessful combination therapy of trichloroacetic acid, podophyllin, and electrocautery on giant condylomata acuminata.
Int J STD AIDS
November 2024
Department of Dermatology, Venereology, and Aesthetics, Dr Mohammad Hoesin General Hospital, Faculty of Medicine Universitas Sriwijaya, Palembang, Indonesia.
Giant condylomata acuminata (GCA) is a rare presentation of anogenital wart (AGW), invasive locally but does not metastasize. Combination therapy for GCA is suggested based on modalities and experiences. The combination of TCA and podophyllin has showed good efficacy, followed by electrocautery to eradicate warts.
View Article and Find Full Text PDFCase Report: Concomitant presence of two STIs in a male patient.
F1000Res
August 2024
Department of Dermatology, Venereology and Leprosy, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, 442001, India.
Article Synopsis
- Syphilis, caused by a spirochaete, spreads through sexual contact or from mother to child, with rising cases linked to risky behaviors like having multiple partners and unprotected sex.
- A case study details a 21-year-old man who had both primary syphilis and genital warts, presenting with a painless ulcer and growths; he was treated effectively according to CDC guidelines.
- The report emphasizes that individuals with multiple partners who don’t use prevention are at higher risk for STIs and calls for improved prevention measures, including early treatment and condom distribution.
Podophyllin Toxicity: Case Report of a Rare Poisoning.
J Assoc Physicians India
July 2024
Medical Officer, Department of Medicine, Deen Dayal Upadhyay Hospital, Delhi, India.
Article Synopsis
- - Podophyllin poisoning is a serious and often fatal emergency that primarily affects the nervous system, caused by a toxic plant resin containing podophyllotoxin, which disrupts cellular functions.
- - Symptoms can take time to appear, leading to potential misdiagnosis as CNS infections or strokes, highlighting the need for high suspicion and quick treatment to avoid severe outcomes.
- - A reported case involved a 23-year-old male who ingested podophyllin, experiencing severe neurological symptoms and multisystem failure resulting in death within four days.
Identification of Epstein-Barr virus after topical treatment for oral hairy leukoplakia: A preliminary study.
Int J STD AIDS
July 2024
Department of Oral Surgery, Pathology and Clinical Dentistry, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Article Synopsis
- The study examined the presence of Epstein-Barr virus type 1 (EBV-1) DNA in HIV patients with oral hairy leukoplakia (OHL) before and after various topical treatments.
- A total of 15 patients received different topical therapies, including podophyllin resin alone or in combination with acyclovir or penciclovir, with samples tested for EBV-1 DNA.
- Results showed clinical healing in all groups, but 73.3% still had EBV-1 detectable after treatment, and some patients experienced recurrences, highlighting a link between treatment type and virus persistence.
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