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Gestational Diabetes Mellitus: Mechanisms Underlying Maternal and Fetal Complications.

Endocrinol Metab (Seoul)

January 2025

Division of Endocrinology and Metabolism, Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.

Gestational diabetes mellitus (GDM) affects over 10% of all pregnancies, both in Korea and worldwide. GDM not only increases the risk of adverse pregnancy outcomes such as preeclampsia, preterm birth, macrosomia, neonatal hypoglycemia, and shoulder dystocia, but it also significantly increases the risk of developing postpartum type 2 diabetes mellitus and cardiovascular disease in the mother. Additionally, GDM is linked to a higher risk of childhood obesity and diabetes in offspring, as well as neurodevelopmental disorders, including autistic spectrum disorder.

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Prevalence trends of type 2 diabetes treatment, dyslipidemia and hepatic steatosis in Northeast Germany.

J Public Health (Oxf)

November 2024

Institute for Community Medicine-SHIP clinical-epidemiological research, University Medicine Greifswald, Greifswald, Germany.

Article Synopsis
  • The study investigates the trends in metabolic cardiovascular risk factors like type 2 diabetes (T2D), dyslipidemia, and hepatic steatosis in Northeast Germany from 2000 to 2012.
  • It found that while treatments for T2D and dyslipidemia increased among adults, the prevalence of dyslipidemia slightly decreased, and hepatic steatosis rose significantly, especially in women and younger individuals.
  • The study emphasizes that promoting healthy diets and obesity control could help prevent these increasing health issues in the region.
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Background: Individuals with diabetes and co-existing psychiatric disorders have more diabetes complications and lower life expectancy than those with diabetes but no co-existing psychiatric disorders. Psychiatric health professionals may have a role in improving these outcomes but often lack diabetes knowledge and skills. This study aims to examine the effectiveness of a diabetes training course for psychiatric health professionals on their diabetes knowledge and skills and clinical outcomes, diabetes support and diabetes distress among individuals with diabetes and psychiatric disorders treated in psychiatric outpatient clinics.

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Introduction: Clinical epidemiological data on monoclonal gammopathy of renal significance (MGRS) are lacking. In this retrospective observational study, MGRS was compared with B-cell or plasma cell malignancies (BCM/PCM) with renal involvement to clarify differences in their clinical features.

Methods: Among the 1408 renal biopsies performed at our hospital, 25 MGRS and 18 BCM/PCM patients were identified.

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Clinical epidemiological and laboratory investigation in co-infection with COVID-19 and tuberculosis.

Rev Inst Med Trop Sao Paulo

November 2024

Universidade Federal de Mato Grosso do Sul, Faculdade de Medicina, Programa de Pós-Graduação em Saúde e Desenvolvimento da Região Centro-Oeste, Campo Grande, Mato Grosso do Sul, Brazil.

Currently, COVID-19 and tuberculosis (TB) are the deadliest infectious diseases worldwide. Their synergy, form of presentation, morbidity, and mortality are data that have been scarcely explored. Thus, this study aimed to characterize the clinical, epidemiological, and laboratory factors of this co-infection and to analyze the factors associated with the active TB among COVID-19 cases.

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