Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/s0076-6879(80)67053-0 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Identification of a bacteria P450 enzyme from B. megaterium H-1 with vitamin D C-25 hydroxylation capabilities.
Enzyme Microb Technol
December 2024
College of Biomass Science and Engineering, Sichuan University, Chengdu 610065, China.
Calcidiol (25(OH)VD) and calcitriol (1α,25(OH)VD) are active vitamin D with high medicinal value, which can maintain calcium and phosphorus balance and treat vitamin D deficiency. Microbial synthesis is an important method to produce high-value-added compounds. It can produce active vitamin D through the hydroxylation reaction of P450, which can reduce the traditional chemical synthesis steps, and greatly improve the production efficiency and economic benefits.
View Article and Find Full Text PDFPhysiological changes in the regulation of calcium and phosphorus utilization that occur after the onset of egg production in commercial laying hens.
Front Physiol
September 2024
Department of Poultry Science, University of Georgia, Athens, GA, United States.
Article Synopsis
- The study investigates the physiological changes in laying hens related to calcium and phosphorus utilization for eggshell formation, specifically looking at the effects of a diet supplemented with 1α-hydroxycholecalciferol (AlphaD3).
- It was found that as hens aged from 18 to 31 weeks, there were significant changes in hormone sensitivity and gene expression linked to calcium and phosphorus regulation, indicating the kidney's increased role in vitamin D processing and bone health during egg production.
- The results showed that hens on the AlphaD3 diet had improved bone quality, with higher mineral density in the humerus and tibia compared to those on a control diet, highlighting the dietary impact on skeletal health
Structural diversification of vitamin D using microbial biotransformations.
Appl Microbiol Biotechnol
July 2024
Research Group BIONUC (Biotechnology of Nutraceuticals and Bioactive Compounds), Departamento de Biología Funcional, Principality of Asturias, Área de Microbiología, Universidad de Oviedo, Oviedo, Spain.
Vitamin D deficiencies are linked to multiple human diseases. Optimizing its synthesis, physicochemical properties, and delivery systems while minimizing side effects is of clinical relevance and is of great medical and industrial interest. Biotechnological techniques may render new modified forms of vitamin D that may exhibit improved absorption, stability, or targeted physiological effects.
View Article and Find Full Text PDFVitamin D metabolism is altered during aging alone or combined with obesity in male mice.
Biofactors
October 2024
Aix-Marseille Université, C2VN, INRAE, INSERM, Marseille, France.
Aging and obesity are associated with a decrease in plasma 25-hydroxyvitamin D (25(OH)D) levels. In the context of a growing aging population and the rising incidence of obesity, we hypothesized that aging process, either independently or in combination with obesity, could influence vitamin D (VD) metabolism, consequently resulting in the reduced 25(OH)D plasma concentrations. C57BL/6JRJ young (6 months) and old (23 months) mice fed with control (CD) or high fat diet (HF) were compared.
View Article and Find Full Text PDFVitamin D deficiency or resistance and hypophosphatemia.
Best Pract Res Clin Endocrinol Metab
March 2024
Department of Endocrinology, Seth G S Medical College and King Edward Hospital, Mumbai 400012, India.
Article Synopsis
- Vitamin D is mostly produced in the skin from sun exposure and is also obtained from food; it's converted into active forms in the liver and kidneys, which are essential for bone health.
- A deficiency in vitamin D, often caused by dietary lack, leads to rickets and osteomalacia, but these conditions can usually be treated with vitamin D supplements.
- Inherited disorders affecting vitamin D metabolism can lead to different types of resistant rickets, characterized by issues like hypophosphatemia, which impairs bone mineralization and can show varying responses to vitamin D supplementation.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!