Pseudomonas ATCC 17483 produced enzymes for naphthalene metabolism when growing in a medium containing succinate and naphthalene. Mutants for naphthalene metabolism produced by treatment with N-methyl-N'-nitro-N-nitrosoguanidine were able to produce these enzymes only when the metabolic pathway was intact as far as salicylaldehyde, which was therefore identified as the first possible inducer.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC293779PMC
http://dx.doi.org/10.1128/jb.141.3.1052-1054.1980DOI Listing

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