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Biophysiochemically favorable, antithrombotic and pro-endothelial coordination compound nanocoating of copper (II) with protocatechuic acid & nattokinase on flow-diverting stents.
Colloids Surf B Biointerfaces
January 2025
Institute of Biomedical Engineering, College of Medicine, Key Laboratory of Advanced Technologies of Materials, Ministry of Education, Southwest Jiaotong University, Chengdu 610031, China. Electronic address:
Neurovascular flow-diverting stents (FDSs) are revolutionizing the paradigm for treatment of intracranial aneurysms, but they still face great challenges like post- implantation acute thrombosis and delayed reendothelialization. Surface modification is of crucial relevance in addressing such key issues. In this study, we fabricated an ultrathin nanocoating out of copper (II) together with protocatechuic acid (PCA) and nattokinase (NK) bioactive molecules on NiTi FDSs via a coordination chemistry approach, with favorable biophysiochemical interactions, to fulfill this goal.
View Article and Find Full Text PDFThe utility of routine intraoperative CSF during ventricular shunt insertion: a 10-year retrospective cohort study.
J Neurosurg Pediatr
January 2025
1Department of Neurosurgery, Queensland Children's Hospital, Brisbane; and.
Objective: Ventricular shunt insertion is a common procedure in pediatric neurosurgical practice. In many areas of medicine there is a push toward rationalization of healthcare resources and a reduction in low-value tests or procedures. The intraoperative sampling of CSF at the time of shunt insertion is one traditional aspect of care that has not been rigorously evaluated.
View Article and Find Full Text PDFVolatile organic compounds from Stenotrophomonas geniculata J-0 as potential biofumigants manage bulb rot caused by Fusarium oxysporum in postharvest Lanzhou lily.
World J Microbiol Biotechnol
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College of Life Science, Northwest Normal University, No.967, Anning East Road, Lanzhou, 730070, People's Republic of China.
The Lanzhou lily bulbs are often vulnerable to postharvest infections by pathogenic fungi, leading to lily bulb rot. This study investigated the ability of volatile organic compounds (VOCs) produced by Stenotrophomonas geniculata J-0 to control the highly pathogenic fungus Fusarium oxysporum BH-7 in postharvest Lanzhou lily bulbs. VOCs of S.
View Article and Find Full Text PDFExploring the morphine-platelet activity association in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention.
Platelets
December 2024
Department of Cardiology, Department of Medical and Health Sciences, Linköping University, Linköping, Sweden.
Article Synopsis
- STEMI is typically triggered by a ruptured plaque, leading to blood clot formation, and treatments like platelet inhibitors and PCI are crucial for recovery.
- This study, part of the VALIDATE-SWEDHEART trial, analyzed 89 STEMI patients to examine how morphine, used for pain relief, affects platelet activity after treatment with ticagrelor and primary PCI.
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Palato-Antral Involvement of a Primary Extracranial Sinonasal Meningioma.
Sultan Qaboos Univ Med J
November 2024
Department of ENT, GSL Medical College, Rajahmundry, India.
Article Synopsis
- - Primary extracranial sinonasal meningiomas are extremely rare tumors in the head and neck area, with limited cases documented, particularly involving the palato-antral region.
- - A 45-year-old male experienced nasal issues like frequent bleeding and blockage for 8 months, leading to a diagnosis of a meningioma that affected his palate; he underwent successful surgery using both intraoral and endoscopic methods.
- - Post-surgery, the patient healed well and has shown no signs of recurrence for over two years; however, accurate diagnosis requires specific immunohistochemistry tests, and complete surgical removal is essential to prevent any recurrence or complications.
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