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A cross-sectional study on improving clinical efficiency through centralized digital impression.
Hua Xi Kou Qiang Yi Xue Za Zhi
February 2025
Center of Stomatology, Peking University Shenzhen Hospital, Shenzhen 518036, China.
Objectives: This study aims to explore the effect of improving clinical efficiency by replacing traditional impression workflow with centralized digital impression workflow.
Methods: The department of prosthodontics in Center of Stomatology, Peking University Shenzhen Hospital has improved the clinical workflow by replacing the traditional impression made by doctors using impression materials for each patient with a centralized digital impression made by one technician for all patients in the department. This cross-sectional study recorded the chairside time required for impression taking in patients undergoing single posterior zirconia full crown restoration before clinical process improvement; the time required for centralized digital impression production; the comfort level of patients; and the adjacency relationship, occlusal contact relationship, and time required for prostheses adjusting (i.
Out-of-Distribution Detection via outlier exposure in federated learning.
Neural Netw
January 2025
Department of Computer Science and Engineering, Inha University, Incheon, South Korea. Electronic address:
Among various out-of-distribution (OOD) detection methods in neural networks, outlier exposure (OE) using auxiliary data has shown to achieve practical performance. However, existing OE methods are typically assumed to run in a centralized manner, and thus are not feasible for a standard federated learning (FL) setting where each client has low computing power and cannot collect a variety of auxiliary samples. To address this issue, we propose a practical yet realistic OE scenario in FL where only the central server has a large amount of outlier data and a relatively small amount of in-distribution (ID) data is given to each client.
View Article and Find Full Text PDFInactivated SARS-CoV-2 induces acute skeletal muscle damage in human K18-hACE2 transgenic mice.
Life Sci
January 2025
Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil. Electronic address:
The pandemic due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) resulted in over 7 million global fatalities and billions of individuals diagnosed with COVID-19. Acute and chronic muscle impairment associated with SARS-CoV-2 infection affected a substantial number of patients, leading to the development of symptoms such as fatigue, muscle pain, and exercise intolerance. Our study introduces an animal model to improve understanding of the pathogenicity caused by SARS-CoV-2 in human skeletal muscle.
View Article and Find Full Text PDFProspective Harmonization, Common Data Elements, and Sharing Strategies for Multicenter Pre-Clinical Traumatic Brain Injury Research in the Translational Outcomes Project in Neurotrauma Consortium.
J Neurotrauma
January 2025
Division of Neuroscience, National Institute of Neurological Disorders and Stroke (NINDS), National Institutes of Health (NIH), Bethesda, Maryland, USA.
Effective team science requires procedural harmonization for rigor and reproducibility. Multicenter studies across experimental modalities (domains) can help accelerate translation. The Translational Outcomes Project in NeuroTrauma (TOP-NT) is a pre-clinical traumatic brain injury (TBI) consortium charged with establishing and validating noninvasive TBI assessment tools through team science.
View Article and Find Full Text PDFGut-resident Tregs (GTregs) play a pivotal role in maintaining bone health under post-menopausal osteoporotic conditions.
J Leukoc Biol
January 2025
Department of Biotechnology, All India Institute of Medical Sciences (AIIMS), New Delhi-110029, India.
Osteoporosis is a skeletal condition characterized by the deterioration of bone tissue. The immune system plays a crucial role in maintaining bone homeostasis and combating the development of osteoporosis. Immunoporosis is the term used to describe the recent convergence of research on the immune system's role in osteoporosis.
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