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Acute Muscle Weakness in Graves' Disease: A Case Report of Hypokalemic Thyrotoxic Periodic Paralysis.
Cureus
November 2024
Emergency Medicine, Mayo Clinic Arizona, Phoenix, USA.
Thyrotoxic periodic paralysis (TPP) is a rare but significant complication of hyperthyroidism, characterized by episodes of muscle weakness or paralysis and associated hypokalemia. This case report details a 30-year-old Latin American male with a history of Graves' disease, presenting with acute muscle weakness and hypokalemia. The patient reported transient episodes of weakness over recent weeks, culminating in a severe episode prompting emergency evaluation.
View Article and Find Full Text PDFSwallowing Assessment in a Pediatric Case of Allan-Herndon-Dudley Syndrome (MCT8 Deficiency): Advanced Insights into Dysphagia via Flexible Endoscopic Evaluation of Swallowing.
Neuropediatrics
January 2025
Division of Pediatric Endocrinology and Diabetology, Department of Pediatrics and Adolescent Medicine, KJF Klinikum Josefinum, Augsburg, Germany.
Patients with MCT8 deficiency often present with underweight and are prone to frequent pulmonary infections, including aspiration pneumonia. Despite commonly reported swallowing difficulties in this population, specific dysphagia symptoms have not been well-documented. We conducted a flexible endoscopic evaluation of swallowing (FEES) on a young boy diagnosed with MCT8 deficiency, who exhibited recurrent pulmonary infections and failed to achieve substantial weight gain despite an oral energy intake appropriate for his age and height.
View Article and Find Full Text PDFPreoperative bilateral recurrent laryngeal nerve palsy in Graves' disease.
BMJ Case Rep
December 2024
Pathology, Juntendo University Shizuoka Hospital, Izunokuni, Shizuoka, Japan.
Clinical Application of Thyrotropin Receptor Antibodies.
Horm Metab Res
December 2024
Department of Endocrinology and Metabolism, Lanzhou University Second Clinical Medical School, Lanzhou, China.
Thyrotropin receptor antibodies (TRAb) are specific for Graves' disease (GD) and play a crucial role in the pathogenesis of GD. TRAb assays have recently been greatly improved. This review discusses the clinical application of TRAb in the differential diagnosis of hyperthyroidism, the prognosis of GD, GD in gestation and pediatrics, and GD related ophthalmopathy (GO).
View Article and Find Full Text PDFThyrotoxic Periodic Paralysis: A Unique Case Highlighting the Diagnostic Challenges and Management.
Cureus
November 2024
Internal Medicine Department, Saint Joseph Hospital, Jerusalem, PSE.
Thyrotoxic periodic paralysis (TPP) is a rare complication primarily associated with thyrotoxicosis, particularly in individuals with Graves' disease. While more common in males aged 20 to 40, it can occur across all ethnic backgrounds. It is the most common type of acquired periodic paralysis.
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