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Hyperkalemia constitutes a constraint for implementing renin-angiotensin-aldosterone inhibition: the widening gap between mandated treatment guidelines and the real-world clinical arena.
Kidney Int Suppl (2011)
April 2016
Division of Nephrology and Hypertension, University of Miami Miller School of Medicine, Miami, Florida, USA.
Recent studies have reported a large gap between the forceful and assertive recommendations in the guidelines and real-world practice in the use of renin-angiotensin-aldosterone inhibitors (RAASi) therapies. A comprehensive, retrospective analysis of a large database of electronic medical records (>7 million patients) was undertaken to evaluate 3 pivotal concerns: (i) whether RAASi are being prescribed according to treatment guidelines, (ii) what happens to RAASi prescriptions after hyperkalemia events, and (iii) what the clinical outcomes are in patients whose RAASi are discontinued or who are prescribed at doses lower than the guidelines recommend. The results indicate that a substantial gap exists between guideline recommendations and real-world prescribing patterns for RAASi.
View Article and Find Full Text PDFElectromyographic Analysis of the Shoulder Girdle Musculature During External Rotation Exercises.
Orthop J Sports Med
November 2015
Musculoskeletal Science Research Group, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.
Background: Implementation of overhead activity, a key component of many professional sports, requires an effective and balanced activation of the shoulder girdle muscles, particularly during forceful external rotation (ER) motions.
Purpose: To identify activation strategies of 16 shoulder girdle muscles/muscle segments during common shoulder ER exercises.
Study Design: Descriptive laboratory study.
Pill Properties that Cause Dysphagia and Treatment Failure.
Curr Ther Res Clin Exp
December 2015
Department of Medicine, University of Iowa; Iowa City, Iowa ; VAMC, Iowa City, Iowa.
Background: Pills (tablets and capsules) are widely used to administer prescription drugs or to take supplements such as vitamins. Unfortunately, little is known about how much effort it takes Americans to swallow these various pills. More specifically, it is not known to what extent hard-to-swallow pills might affect treatment outcomes (eg, interfering with adherence to prescribed medications or causing clinical complications).
View Article and Find Full Text PDF[Tai ping sheng hui fang (Taiping Holy Prescriptions for Universal Relief) and the compilation during the early Song Dynasty].
Zhonghua Yi Shi Za Zhi
July 2010
The Institute for the History of Natural Science, China Academy of Sciences, Beijing, 100010, China.
Tai ping sheng hui fang, the first medical formulary of the Song Dynasty, compiled from the 3(rd) year of Taiping-xingguo reign to the 3(rd) year of Chunhua reign (978 ∼ 992), under the edict of the Taizong Emperor, was popularly applied and extensively circulated and called "the first formulary of the Dynasty". It is extremely significant in the medical history of the Song Dynasty due to its theory of prescription art, practical prescriptions and clinical practice. During the process of its circulation, different versions appeared, including the Guozijian Orthodox Version, Guozijian Small-character Version, Chongwen Hall Abridged Version, Newly Carved Version of Zhuanyunsi, and the Local Abridged Version, thus adapting to the demands of various walks of life in the society.
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