Duplex scanning provides real time B-mode images of the carotid bifurcation vessels along with a single gate pulsed Doppler flow velocity detector. By using the B-mode output of the duplex system to measure the Doppler angle and spectrum analysis to measure the frequency content of the Doppler signal, instantaneous flow velocity can be calculated. Mean velocity at peak systole was calculated retrospectively in 68 common (CCA) and internal (ICA) carotid arteries of 39 patients who had undergone prior angiography and prospectively in 30 arteries of 15 healthy young controls. The ratio of mean peak ICA velocity to mean peak CCA velocity at systole (VICA/VCCA) was below 0.8 in all 36 normal arteries and above 1.5 in all 21 high-grade stenoses of 60% or greater diameter reduction. Sixty-one percent of 41 vessels with less than 10 to 55% diameter reduction had a velocity ratio between 0.8 and 1.5. Only 10% of all ICA's with any stenotic lesion were incorrectly classified as normal. VICA/VCCA appears to be an accurate indicator of the degree of ICA stenosis.
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http://dx.doi.org/10.1161/01.str.11.1.67 | DOI Listing |
Sci Rep
January 2025
University of Ulsan, 93 Daehak-ro, Nam-gu, Ulsan, 680-749, Republic of Korea.
This study employed large eddy simulation (LES) with the wall-adapting local eddy-viscosity (WALE) model to investigate transitional flow characteristics in an idealized model of a healthy thoracic aorta. The OpenFOAM solver pimpleFoam was used to simulate blood flow as an incompressible Newtonian fluid, with the aortic walls treated as rigid boundaries. Simulations were conducted for 30 cardiac cycles and ensemble averaging was employed to ensure statistically reliable results.
View Article and Find Full Text PDFMagn Reson Imaging
January 2025
Institute of Fluid Mechanics, University of Rostock, Rostock, Germany.
Purpose: To improve the current method for MRI turbulence quantification which is the intravoxel phase dispersion (IVPD) method. Turbulence is commonly characterized by the Reynolds stress tensor (RST) which describes the velocity covariance matrix. A major source for systematic errors in MRI is the sequence's sensitivity to the variance of the derivatives of velocity, such as the acceleration variance, which can lead to a substantial measurement bias.
View Article and Find Full Text PDFUltrasonics
January 2025
The Center for Fast Ultrasound Imaging, Department of Health Technology. Technical University of Denmark, Ørsteds Plads Building 349, Lyngby, DK-2800, Denmark.
Non-invasive estimation of pressure differences using 2D synthetic aperture ultrasound imaging offers a precise, low-cost, and risk-free diagnostic tool. Unlike invasive techniques, this preserves natural blood flow and avoids the limitations of devices that occupy lumen space. This paper evaluates a previously published estimator, modified to incorporate Singular Value Decomposition (SVD) echo-cancellation, using data from ten healthy volunteers and one patient.
View Article and Find Full Text PDFJ Chromatogr A
January 2025
Institute for Bioengineering, School of Engineering, The University of Edinburgh, Edinburgh, EH9 3BF, United Kingdom.
Traditional packed beds in chromatography suffer from increased band broadening due to the random nature of packing, leading non-ideal fluid flow and channeling. To address these challenges, pillar array columns have been developed, offering improved performance over random packing thanks to their homogenous fluid profiles. The study aims to i) evaluate fluid dynamics and chromatographic performance across different PAC morphologies, ii) establish the influence of column morphology on performance, and iii) assess the correlation between chromatographic performance and hydrodynamic parameters.
View Article and Find Full Text PDFSci Total Environ
January 2025
Center for Marine Sensors, Institute for Chemistry and Biology of the Marine Environment (ICBM), Carl von Ossietzky University of Oldenburg, 26382 Wilhelmshaven, Germany.
Microplastics (MP) are known to be ubiquitous. The pathways and fate of these contaminants in the marine environment are receiving increasing attention, but still knowledge gaps exist. In particular, the link between mass-based MP quantification and oceanographic parameters is often lacking.
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