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The Efficacy of Shear Wave Elastography in Evaluating Treatment Response to US-Guided Steroid Injection in Patients with Carpal Tunnel Syndrome.
Acad Radiol
January 2025
Department of Orthopedics and Traumatology, Samsun University Faculty of Medicine, Samsun, Turkey (A.E.O.).
Rationale And Objectives: This study aimed to evaluate the efficacy of ultrasound (US)-guided local steroid injection in carpal tunnel syndrome (CTS) using shear wave elastography (SWE).
Materials And Methods: A total of 47 wrists from 41 patients diagnosed with mild to moderate idiopathic CTS, based on clinical and electrophysiological criteria, were enrolled between June and October 2024. All participants underwent US-guided local steroid injection.
Individualized Spectral Features in First-episode and Drug-naïve Major Depressive Disorder: Insights from Periodic and Aperiodic EEG Analysis.
Biol Psychiatry Cogn Neurosci Neuroimaging
January 2025
School of Biomedical Sciences and Engineering, South China University of Technology, Guangzhou 511442, China; National Engineering Research Center for Tissue Restoration and Reconstruction, South China University of Technology, Guangzhou 510006, China; Guangdong Province Key Laboratory of Biomedical Engineering, South China University of Technology, Guangzhou 510006, China; Department of Nuclear Medicine and Radiology, Institute of Development, Aging and Cancer, Tohoku University, Sendai 980-8575, Japan. Electronic address:
Background: The detection of abnormal brain activity plays an important role in the early diagnosis and treatment of major depressive disorder (MDD). Recent studies have shown that the decomposition of the electroencephalography (EEG) spectrum into periodic and aperiodic components is useful for identifying the drivers of electrophysiologic abnormalities and avoiding individual differences.
Methods: This study aimed to elucidate the pathologic changes in individualized periodic and aperiodic activities and their relationships with the symptoms of MDD.
Biomarkers.
Alzheimers Dement
December 2024
Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA; NYU Langone Health, New York, NY, USA.
Background: Clinical and preclinical evidence suggest that abnormal electrical activity strongly impacts outcomes in Alzheimer's disease (AD). Indeed, AD patients with interictal spikes (IIS) show faster cognitive decline than those without IIS. Furthermore, seizures in patients with AD have been suggested to accelerate disease progression.
View Article and Find Full Text PDFBackground: Recent developments in physiological and digital biomarkers provide an opportunity to shift the first diagnostic steps to the home-setting, thus allowing earlier detection and treatment of Alzheimer's disease (AD). Blood-based, magnetic resonance imaging, electrophysiological, digital and microbiome biomarkers have shown great promise and call for an evaluation of their accuracy, feasibility and safety in primary care and the community. The aim of PREDICTOM is to develop and test the accuracy of an artificial intelligence (AI) driven screening platform for the prediction and early detection of AD and to extend the clinical pathway to home-based screening using established and novel biomarkers.
View Article and Find Full Text PDFBiomarkers.
Alzheimers Dement
December 2024
Alzheimer Research Centre KU Leuven, Leuven Brain Institute, Leuven, Belgium.
Background: In Alzheimer disease (AD) changes in the small world network have been described, which can be considered as the balance between local connectivity, exhibited with the "clustering coefficient", and global integration, investigated by "characteristic path length". With high-density EEG, we examined the effect of early spread of tau aggregates on these global graph measures.
Method: This study includes 47 participants who underwent a 100-minute dynamic F-MK6240 PET-scan and a five-minutes eyes closed 128-channel resting-state EEG.
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