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Indobufen versus aspirin in patients with indication for antiplatelet therapy: A systematic review and meta-analysis.
Vascul Pharmacol
January 2025
INC Hospital, Curitiba, Brazil. Electronic address:
Introduction: Aspirin is commonly recommended for individuals who have experienced stroke or myocardial infarction (MI). Indobufen, a cyclooxygenase-1 inhibitor, has been studied as a potential alternative. We conducted a meta-analysis and trial sequential analysis (TSA) to compare indobufen with aspirin in patients requiring antiplatelet therapy.
View Article and Find Full Text PDFLung seven transmembrane receptors are involved in Arabidopsis root growth mediated by Danger-associated peptide Pep1.
Biochem Biophys Res Commun
January 2025
State Key Laboratory for Pharmaceutical Biotechnology, College of Life Sciences, Nanjing University, 210093, Nanjing, China.
Lung seven transmembrane receptor family is a small part of Arabidopsis gene family. So far, the function of some members of the this family is unknown. Plant elicitor peptide1 (Pep1) is one of damage-associated molecular patterns (DAMPs), which could trigger root growth inhibition and plant immunity responses.
View Article and Find Full Text PDFAllergic Rhinitis and Its Associated Co-Morbidities Among Patients Attending the ENT Department at Kilimanjaro Christian Medical Center in Northern Tanzania: Cross-Sectional Study.
Immun Inflamm Dis
January 2025
Department of Medicine, Kilimanjaro Christian Medical University College, Moshi, Tanzania.
Introduction: Allergic rhinitis is the specific inflammation against allergen by immune defense cells on the nasal mucosa, which can lead to chronic nasal symptoms such as sneezing, itching, runny nose, and nasal congestion. It is associated with high morbidity including sinusitis, asthma, otitis media, hypertrophied inferior turbinate, and nasal polyps. Despite its complications, it remains poorly recognized and tracked.
View Article and Find Full Text PDFGlial activation and nociceptive neuropeptide elevation associated with the development of chronic post-traumatic headache following repetitive blast exposure.
Neurobiol Pain
December 2024
Virginia Polytechnic Institute and State University. Department of Biomedical Engineering, 325 Stranger St., Blacksburg, VA 24060, United States.
Chronic headaches and pain are prevalent in those who are exposure to blast events, yet there is a gap in fundamental data that identifies the pathological mechanism for the chronification of pain. Blast-related post-traumatic headaches (PTH) are understudied and chronic pain behaviors in preclinical models can be vital to help elucidate PTH mechanisms. The descending pain modulatory system controls pain perception and involves specific brain regions such as the cortex, thalamus, pons, and medulla.
View Article and Find Full Text PDFA comprehensive review on anti-allergic natural bioactive compounds for combating food allergy.
Food Res Int
February 2025
School of Food Science and Engineering, Qingdao Agricultural University, Qingdao 266109, PR China. Electronic address:
Food allergy poses a great challenge to food safety and public health worldwide. Currently, clinical symptoms are primarily managed with medications, which can lead to drug resistance, adverse effects, and disruptions in gut flora balance. As a result, there has been a focus on researching safe and effective anti-allergic natural ingredients.
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