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Article Synopsis
  • This study focuses on analyzing the CT and MR imaging characteristics of intracranial extra-axial chondromas in six patients, highlighting their distinct appearances based on location.
  • The researchers found that frontal chondromas typically showed calcification and mixed signals on imaging, while cavernous sinus chondromas displayed bone erosion and intense hyperintensity on T2-weighted images without calcification.
  • The study concludes that while there are various imaging features, specific traits like absence of restricted diffusion and distinct signal patterns can suggest the presence of an intracranial chondroma, aiding in diagnosis.
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Background: Intracranial chondroma is an extremely rare type of tumor composed of mature hyaline cartilaginous tissues. No previous cases of skull base periosteal chondroma have been presented.

Observations: A 31-year-old male had progressive memory loss and diminished motivation for the previous 1.

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Intracranial chondroid tumors are a heterogeneous group of neoplasms characterized by the presence of a cartilage matrix. These tumors exhibit overlapping clinical and histological features. Mutations in genes serve as important diagnostic markers of tumor type, particularly chondrosarcoma.

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Intracranial Chondroma of Cranial Vault.

Radiol Imaging Cancer

March 2023

From the Department of Radiology, West Virginia University, 1 Medical Center Dr, Morgantown, WV 26506 (D.A.L., R.I.M.).

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Objective: To improve the diagnosis and treatment of intracranial chondromas (ICDs) by discussing the clinical manifestations and imaging characteristics of ICDs, as well as surgical methods and treatment strategies.

Methods: We retrospectively analyzed 17 patients diagnosed with ICDs who underwent microsurgery or endoscopic transsphenoidal surgery at the Tangdu Hospital of Air Force Military Medical University and the Mianyang Central Hospital from January 2010 to November 2021. Clinical manifestations, imaging examinations, surgical treatments, and prognosis of these patients were analyzed.

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