Since June 1977 to June 1980 screening program for neonatal hypothyroidism was carried out in the area of Vicence. 6.340 newborns were screening, in the fifth day of life, primarily by measuring T4 levels, later by measuring both T4 and TSH levels in the blood serum. Three babies were proved to have neonatal hypothyroidism: two cases showed athyreotic hypothyroidism, and one case was due to familial thyroid dyshormonogenesis. The incidence of this condition in our area is much higher than 1:3.000 newborns. Two cases of familial deficit of thyroxine-binding globulin and two subjects with partial enzymatic deficiency were also detected.
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