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The presence of unknown polio engagement confirmed by electromyography and muscle testing.
J Rehabil Med
January 2025
Borås hospital, Region Västra Götaland, Borås, Sweden; Department of Rehabilitation medicine, Sahlgrenska University Hospital, Gothenburg, Sweden.
Objective: To evaluate the usefulness of electromyography at a polio clinic in identifying unperceived muscle denervation. Second, to compare people who perceived themselves as weak in 1 or both legs with those who did not.
Design: Cross-sectional study.
Immunodeficiency-Related Vaccine-Derived Poliovirus (iVDPV) Infections: A Review of Epidemiology and Progress in Detection and Management.
Pathogens
December 2024
World Health Organization Headquarters, Av Appia 10, 1211 Geneva, Switzerland.
Individuals with certain primary immunodeficiency disorders (PID) may be unable to clear poliovirus infection after exposure to oral poliovirus vaccine (OPV). Over time, vaccine-related strains can revert to immunodeficiency-associated vaccine-derived poliovirus (iVDPVs) that can cause paralysis in the patient and potentially spread in communities with low immunity. We reviewed the efforts for detection and management of PID patients with iVDPV infections and the epidemiology through an analysis of 184 cases reported to the World Health Organization (WHO) during 1962-2024 and a review of polio program and literature reports.
View Article and Find Full Text PDFTotal knee arthroplasty in patient with poliomyelitis sequelae: maintaining a recurvatum is associated with better mid-term functional results.
Arch Orthop Trauma Surg
December 2024
Department of Orthopaedic and Trauma Surgery, Raymond-Poincaré Hospital, APHP, Garches, France.
Purpose: Total knee arthroplasty (TKA) in patients with sequelae of poliomyelitis is a surgical challenge due to muscle weakness, bone deformities or post-polio syndrome (PPS). Few data exist to determine the factors contributing to poor functional results. This study aimed: (1) to describe a cohort of patients with poliomyelitis sequelae who underwent TKA; (2) to examine risk factors for poor functional outcome.
View Article and Find Full Text PDFRetrospective, cross-sectional study of the determinants of acute flaccid paralysis among children in Pakistan.
East Mediterr Health J
September 2024
Medical Teaching Institute, Lady Reading Hospital, Peshawar, Pakistan.
Background: Timely diagnosis of acute flaccid paralysis is very crucial in developing countries like Pakistan, because this will have significant impact on management.
Aim: To assess the surveillance, aetiology and epidemiology of acute flaccid paralysis in a tertiary care hospital in Peshawar, Pakistan.
Methods: This retrospective, observational study was conducted at the Paediatric Department of Lady Reading Hospital, Peshawar, in 2022.
Exploring the Phenotypic Profile of Acute Flaccid Paralysis: Insights from a Third-Level Pediatric Emergency Room.
Iran J Child Neurol
September 2024
Pediatric Neurologist, Myelin Disorders Clinic, Pediatric Neurology Division, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
Article Synopsis
- The study focused on diagnosing Acute Flaccid Paralysis (AFP) in children referred to a pediatric emergency unit between 2011 and 2016.
- The most common diagnoses were Guillain-Barré Syndrome (80 cases), acute viral myositis (20 cases), Transverse Myelitis Syndrome (6 cases), and Vaccine-Associated Paralytic Poliomyelitis (6 cases), with all patients testing negative for poliovirus.
- A unique case of a 2.5-month-old patient presented with symptoms compatible with viral meningitis, highlighting the importance of considering a range of diagnoses when evaluating AFP in children.
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