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Gut-derived lactic acid enhances tryptophan to 5-hydroxytryptamine in regulation of anxiety via .
Gut Microbes
December 2025
MOE/NHC/CAMS Key Lab of Medical Molecular Virology, School of Basic Medical Sciences, & National Clinical Research Center for Aging and Medicine, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
The gut microbiota plays a pivotal role in anxiety regulation through pathways involving neurotransmitter production, immune signaling, and metabolic interactions. Among these, gut-derived serotonin (5-hydroxytryptamine, 5-HT), synthesized from tryptophan metabolism, has been identified as a key mediator. However, it remains unclear whether specific microbial factors regulate tryptophan metabolism to influence 5-HT production and anxiety regulation.
View Article and Find Full Text PDFEffects of the music tempo during walking exercise on heart rate variation, lactic acid, and aerobic variables in male college students.
J Exerc Rehabil
December 2024
Department of Kinesiology, College of Natural Science, Jeju National University, Jeju, Korea.
The purpose of this study is to investigate the effects of music tempo on heart rate (HR), HR variability (HRV), lactate levels, and aerobic capacity during walking exercise in male college students. Ten male college students randomly participated in three experiments using various music tempos on a treadmill device to prevent data contamination between measurements by allowing a 2-week interval. Walking exercise was performed at a moderate intensity of 60%-70% maximum HR for 30 min, with participants divided into three groups based on music tempo: exercise group with fast tempo music (ExF, 120-160 bpm), exercise group with slow tempo music (ExS, 60-70 bpm), and exercise group without music (Ex).
View Article and Find Full Text PDF[Construction of prognostic prediction model for patients with sepsis-induced acute kidney injury treated with continuous renal replacement therapy].
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
December 2024
Department of Urology, Fuyang People's Hospital, Fuyang 236000, Anhui, China. Corresponding author: Li Dongfeng, Email:
Objective: To explore the influencing factors of prognosis in patients with sepsis-induced acute kidney injury undergoing continuous renal replacement therapy (CRRT), and to construct a mortality risk prediction model.
Methods: A retrospective research method was adopted, patients with sepsis-induced acute kidney injury who received CRRT at Fuyang People's Hospital from February 2021 to September 2023 were included in this study. Collect general information, comorbidities, vital signs, laboratory indicators, disease severity scores, treatment status, length of stay in the intensive care unit (ICU), and 28-day prognosis were collected within 24 hours of patient enrollment.
[Analysis of the correlation between driving pressure and prognosis in lung transplant recipients based on restricted cubic spline model].
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
December 2024
Department of Critical Care Medicine, the Affiliated Wuxi People's Hospital of Nanjing Medical University (Wuxi People's Hospital), Wuxi 214023, Jiangsu, China.
Objective: To investigate the correlation between postoperative driving pressure (DP) and the prognosis of lung transplantation, and to further evaluate the value of early DP monitoring in lung transplantation.
Methods: A observational study was conducted. The patients after lung transplantation who admitted to the intensive care unit (ICU) of Wuxi People's Hospital from February 1, 2022 to February 1, 2023 were collected.
Transfusion-transmitted bacterial infection risk due to the proliferation of psychrotrophic bacterial species in RBCs and their difficulty in detection.
Transfusion
January 2025
Japanese Red Cross Society, Central Blood Institute, Tokyo, Japan.
Background: Reports of cases of bacterial infection due to transfusion of red blood cell (RBC) components (RBC-TTBI) are relatively rare. Hence, the possibility of undetectable bacterial contamination in RBCs, especially by psychrotrophic bacteria, must be clarified.
Study Design And Methods: We assessed nine psychrotrophic bacterial species, including those implicated in bacteremia or RBC-TTBIs.
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