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Transcriptomic and Biochemical analysis of Procambarus clarkii upon exposure to Pesticides: Population-Specific responses as a sign of pollutant resistance?
Environ Res
January 2025
UMR-MARBEC, Université de Montpellier, CNRS, Ifremer, IRD, Place Eugène Bataillon, Montpellier 34095, France; Australian Rivers Institute, Griffith University, Gold Coast, 4215 Queensland, Australia. Electronic address:
The effects that anthropogenic stressors may have on modulating species' plasticity has been relatively unexplored; however, it represents a scientific frontier that may offer insights into their ability to colonize new habitats. To explore the advantage that inhabiting polluted environments may offer to invasive species, we selected the crayfish Procambarus clarkii, a species that can colonize and thrive in a wide range of aquatic environments, including heavily polluted ones. Here, we studied the molecular and physiological responses of crayfish when experimentally exposed to a pesticide mix of azoxystrobin and oxadiazon at sublethal concentrations.
View Article and Find Full Text PDFMulti-signal fluorescent probe for simultaneous differentiation and imaging of Hg, Cys, Hcy, and GSH in living cells and zebrafish.
J Hazard Mater
January 2025
Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research (Ministry of Education), Institute of Interdisciplinary Studies, College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha 410081, PR China. Electronic address:
The Mercury (II) ion (Hg²⁺) is a toxic heavy metal that threatens biological systems by inducing oxidative stress and disrupting the redox balance. Biothiols such as cysteine (Cys), homocysteine (Hcy), and glutathione (GSH) are critical in maintaining redox homeostasis and are implicated in numerous physiological and pathological processes. Understanding the complex interactions between Hg²⁺ and biothiols requires molecular tools capable of simultaneous detection.
View Article and Find Full Text PDFA case-control genome-wide association study of estimated breeding values for resistance to gastrointestinal nematodes in two local dairy sheep breeds.
Animal
December 2024
University of Molise, Department of Agricultural, Environmental and Food Science, Campobasso, Italy.
In sheep, gastrointestinal nematodes (GINs) can cause disease, reduced feed intake, and nutritional deficiencies. To counteract GINs, anthelmintics are widely used although it is well known they may enter the environment impacting ecosystems. In addition, anthelmintics resistance has rapidly developed and consequently, alternative approaches are crucial for profitable and sustainable sheep production.
View Article and Find Full Text PDFNovel methods for the detection of glutathione by surface-enhanced Raman scattering: A perspective review.
Heliyon
January 2025
Department of Chemical Engineering, Fahd University of Petroleum & Minerals (KFUPM), Dhahran, 31261, Kingdom of Saudi Arabia.
Article Synopsis
- Detection of Glutathione (GSH) is crucial for understanding antioxidant capacity and its links to health conditions, including cancer, where higher levels may confer treatment resistance.
- Various techniques exist for measuring GSH, with surface-enhanced Raman scattering (SERS) being highlighted as an effective method for biomolecule detection.
- The review discusses two SERS-based methods for detecting GSH (heat-induced and reversed reporting agent) and emphasizes the importance of optimizing various parameters for improved detection efficiency in real-time applications.
Baseline Vitamin D Levels on Quality of Life and Pain Perception Among Patients with Chronic Pain with Long-Term Prescription Opioid Use: A Prospective Study.
J Clin Med
January 2025
Clinic of Anaesthesiology and Intensive Care, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, LT-03101 Vilnius, Lithuania.
To investigate the correlation between baseline serum concentrations of 25-hydroxyvitamin D (25-OHD) and quality of life (QoL), as well as pain perception in patients with chronic pain with long-term prescription opioid usage before opioid detoxification. We prospectively studied 45 patients with chronic pain with long-term prescription opioid usage who were selected for elective detoxification. Baseline serum 25-OHD levels were measured prior to detoxification, classifying patients as either vitamin D deficient (<75 nmol/L) or sufficient (≥75 nmol/L).
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