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Carcinoma of the oesophagus associated with membrano-proliferative glomerulonephritis. | LitMetric

AI Article Synopsis

  • Nephrotic syndrome can be linked to various cancers, and this report highlights its occurrence with esophageal carcinoma due to membranoproliferative glomerulonephritis.
  • Initially, the patient had proteinuria prior to tumor removal, but the full nephrotic syndrome developed afterwards and later resolved, resulting in clear urine and improved kidney health.
  • The report discusses potential mechanisms that could explain how nephrotic syndrome developed in this patient with esophageal cancer.

Article Abstract

Nephrotic syndrome has been observed in association with different types of neoplasia. This appears to be the first report of the occurrence of the nephrotic syndrome due to membrano proliferative glomerulonephritis in association with carcinoma of the oesophagus. Although proteinuria was present before excision of the tumour, the nephrotic phase occurred subsequently. Eventually it disappeared leaving the patient with a clear urine and biochemical and histological improvement of the renal lesion (including immunofluorescent and electronmicroscopy studies). Possible mechanisms responsible for the nephrotic syndrome in this case are discussed.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2426166PMC
http://dx.doi.org/10.1136/pgmj.57.671.592DOI Listing

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