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Comprehensive Analysis of the Spectrum of Osteoarticular Infections in Children.
J Pediatric Infect Dis Soc
January 2025
Department of Pediatrics, University of Connecticut School of Medicine, Farmington, CT, USA.
Background: Studies of pediatric osteoarticular infections (OAIs) mostly focus on acute hematogenous osteomyelitis (AHO) and acute bacterial arthritis (ABA). A comprehensive descriptive analysis of pediatric OAIs, including subacute, chronic, and non-hematogenous types, is lacking.
Methods: A detailed analysis of all pediatric OAIs was undertaken at two academic centers, Hasbro Children's Hospital, Providence, RI, and Nationwide Children's Hospital, Columbus, OH.
Joint fluid multi-omics improves diagnostic confidence during evaluation of children with presumed septic arthritis.
Pediatr Rheumatol Online J
January 2025
Department of Immunology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Background: An accurate diagnosis of septic versus reactive or autoimmune arthritis remains clinically challenging. A multi-omics strategy comprising metagenomic and proteomic technologies were undertaken for children diagnosed with presumed septic arthritis to advance clinical diagnoses and care for affected individuals.
Methods: Twelve children with suspected septic arthritis were prospectively enrolled to compare standard of care tests with a rapid multi-omics approach.
REPRINTED FROM THE 2023 HYPERBARIC INDICATIONS MANUAL 15 Edition:Intracranial Abscess.
Undersea Hyperb Med
January 2025
The term "intracranial abscess" (ICA) includes cerebral abscess, subdural empyema, and epidural empyema, which share many diagnostic and therapeutic similarities and, frequently, very similar etiologies. Infection may occur and spread from a contiguous infection such as sinusitis, otitis, mastoiditis, or dental infection; hematogenous seeding; or cranial trauma. Brain abscess usually results from predisposing factors such as HIV infection, immunosuppressive drug treatment, surgery, adjacent infection (i.
View Article and Find Full Text PDFPrevalence of Complications Due to Transphyseal Hematogenous Osteomyelitis.
J Bone Joint Surg Am
December 2024
Pediatric Orthopaedic Unit, Pediatric Surgery Service, Geneva University Hospitals, Geneva, Switzerland.
Background: Transphyseal hematogenous osteomyelitis (THO) is a common infectious condition, being present in 25% of patients with hematogenous osteomyelitis. A large proportion of pediatric hematogenous osteomyelitis infections can spread through the growth cartilage and therefore may be potentially responsible for growth disorders, leading to limb-length discrepancy or angular deformities. The purpose of the present study was to identify both the prevalence of complications caused by transphyseal osteomyelitis and factors influencing their occurrence.
View Article and Find Full Text PDFIliopsoas Abscess Related to Pseudomonas aeruginosa: A Case Report.
Cureus
October 2024
Department of Internal Medicine, Fukui General Hospital, Fukui, JPN.
We describe a rare case of an 80-year-old male with an iliopsoas abscess (IPA) associated with (). The patient had a history of diabetes mellitus and was admitted to our hospital due to aspiration pneumonia, where he was treated with ampicillin/sulbactam (ABPC/SBT). After admission, he experienced a recurrence of aspiration pneumonia, and ABPC/SBT was repeatedly used.
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