[Psychopathology of acute organophosphorus compound poisonings].

Zh Nevropatol Psikhiatr Im S S Korsakova

Published: March 1982

AI Article Synopsis

  • The study examined 65 patients who were poisoned by organophosphorus insecticides, noting various psychotic symptoms.
  • Key symptoms included psychovegetative, psychovestibular, and hyperkinetic, which evolved throughout the course of poisoning.
  • Atropine treatment resulted in a drug-induced psychosis similar to oneiroid syndrome, making it important to differentiate this from poisoning-induced psychosis based on clinical and laboratory findings.

Article Abstract

Under examination there were 65 patients with poisoning with organophosphorus insecticides (thiophos, carbophos, chlorophos). The leading psychotic symptoms in these intoxications were psychovegetative, psychovestibular and hyperkinetic ones, which transformed into each other, as the poisoning progressed. The therapeutic applications of atropine led to development of a drug psychosis resembling the oneiroid syndrome. While making the diagnostic differentiation between the latter and the psychosis due to the poisoning with organophosphorus insecticides one should take into account the clinical and laboratory findings.

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