The studies were carried out at Dzhermuk clinical sanatorium in 53 patients with moderate and severe diabetes mellitus. Qualitative and quantitative phospholipid content of the whole blood and total cholesterol and beta-lipoproteins of the blood serum were determined. The patients show the constant qualitative content of the blood phospholipids and marked quantitative variations in several phospholipid fractions along with a relatively stable condition of other lipid metabolism indices. The degree of phospholipid fraction quantitative disorders is dependent on the patient's age and diabetes mellitus severity, lipid-lipoid ratio tending to decrease in the neutral phospholipid per cent content of the total phospholipid sum. The treatment at the health resort is accompanied by normalization or a tendency to normalize the blood phospholipid quantitative content and lipid-lipoid ratio. The treatment efficiency is directly dependent on the patient's age, duration and severity of the disease.

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