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Dermatofibrosarcoma protuberans: A rare presentation in the scalp. Case report.
Stomatologija
July 2023
RYA COSMO Foundation Hospital, Chennai, India.
Background: Dermatofibrosarcoma protuberans of the scalp (DFSP) is a rare soft tissue neoplasm originating from the dermal layer of the skin, usually affecting the adults.
Case Report: The current case report presents a 48-year old male with a huge lump on the right side of parietal region. A wide local excision of the tumor was performed and the excised specimen was sent for histopathological examination.
DICER1-associated central nervous system sarcoma with neural lineage differentiation: a case report.
Diagn Pathol
September 2022
Department of Pathology, Sanbo Brain Hospital, Capital Medical University, No.50 Xiangshan Yikesong Road, Haidian District, 100093, Beijing, China.
Background: DICER1-associated central nervous system sarcoma (DCS) without evidence of other cancer-related syndromes is rare. Though the morphology of DCS was highly variable, the immunophenotype was predominant myogenic phenotype. Other lineage markers were consistently negative.
View Article and Find Full Text PDF[Malignant solitary fibrous tumors: a clinicopathological and molecular genetic analysis].
Zhonghua Bing Li Xue Za Zhi
June 2022
Department of Pathology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
To explore the clinicopathological features, immunophenotype and molecular genetic characteristics of malignant solitary fibrous tumor (MSFT). Seven cases of MSFT were collected from the First Affiliated Hospital of Zhengzhou University from July 2018 to December 2020. Immunohistochemistry, RNA-based NGS and DNA-based NGS were performed.
View Article and Find Full Text PDFPrimary central nervous system sarcomas in adults: A systematic review.
Clin Neurol Neurosurg
March 2022
Department of Neurological Surgery, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Background: Primary central nervous system (CNS) sarcomas represent a heterogeneous group of rare neoplasms with unclear etiology. Available data on clinical characteristics, treatment strategies, and survival are scarce. We comprehensively reviewed management strategies and outcomes of primary CNS sarcomas in adults.
View Article and Find Full Text PDFGliosarcoma in patients under 20 years of age. A clinicopathologic study of 11 cases and detailed review of the literature.
BMC Pediatr
February 2021
Department of Pathology and Laboratory Medicine, Section of Histopathology, Aga Khan University Hospital, Karachi, Pakistan.
Background: Gliosarcoma is a rare variant of IDH- wild type glioblastoma with both glial and mesenchymal differentiation. It accounts for approximately 2% of glioblastomas and has a poor prognosis similar to that of classic glioblastoma. It is seen mostly between 40 and 60 years of age with a mean age over 50 years.
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