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Optically Controlled Drug Delivery Through Microscale Brain-Machine Interfaces Using Integrated Upconverting Nanoparticles.
Sensors (Basel)
December 2024
Research Group for Implantable Microsystems, Faculty of Information Technology & Bionics, Pázmány Péter Catholic University, H-1083 Budapest, Hungary.
The aim of this work is to incorporate lanthanide-cored upconversion nanoparticles (UCNP) into the surface of microengineered biomedical implants to create a spatially controlled and optically releasable model drug delivery device in an integrated fashion. Our approach enables silicone-based microelectrocorticography (ECoG) implants holding platinum/iridium recording sites to serve as a stable host of UCNPs. Nanoparticles excitable in the near-infrared (lower energy) regime and emitting visible (higher energy) light are utilized in a study.
View Article and Find Full Text PDFExploring the Utility of the Muse Headset for Capturing the N400: Dependability and Single-Trial Analysis.
Sensors (Basel)
December 2024
Psychology Department, Middle Tennessee State University, Murfreesboro, TN 37132, USA.
Consumer-grade EEG devices, such as the InteraXon Muse 2 headband, present a promising opportunity to enhance the accessibility and inclusivity of neuroscience research. However, their effectiveness in capturing language-related ERP components, such as the N400, remains underexplored. This study thus aimed to investigate the feasibility of using the Muse 2 to measure the N400 effect in a semantic relatedness judgment task.
View Article and Find Full Text PDFExploring the Link Between Interoception and Symptom Severity in Premature Ventricular Contractions.
J Clin Med
December 2024
National Medical Research Center for Therapy and Preventive Medicine, Ministry of Healthcare of the Russian Federation, 101000 Moscow, Russia.
: The physiological basis underlying symptomatic versus asymptomatic premature ventricular contractions (PVCs) remains poorly understood. However, symptomatic PVCs can significantly impair quality of life. In patients without structural heart disease, symptom intensity is crucial for guiding management strategies and determining the need for medical or surgical intervention.
View Article and Find Full Text PDFTympanic Pre-Operative Electrically Evoked Auditory Late Response (TympEALR) as an Alternative to Trans-Tympanic Tests Using Anesthesia in Cochlear Implant Candidacy.
J Clin Med
December 2024
Section Cochlear Implantation, Department of Otorhinolaryngology, University Hospital of Munich (LMU), 81377 Munich, Germany.
: Before a cochlear implant is considered, patients undergo various audiological tests to assess their suitability. One key test measures the auditory brainstem response (ABR) to acoustic stimuli. However, in some cases, even with maximum sound stimulation, no response is detected.
View Article and Find Full Text PDFAssessment of the Peripheral and Central Auditory System in Infants Whose Mothers Tested Positive for COVID-19 During Pregnancy.
Children (Basel)
December 2024
School of Medical Sciences, State University of Campinas, Campinas 13083-887, Brazil.
Introduction: Coronavirus disease 2019 (COVID-19) is an infectious disease caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), a new member of the coronavirus family. While respiratory transmission is the main route, concerns have arisen regarding possible vertical transmission, which refers to the transmission of the virus from mother to fetus through the dissemination of viral particles in the amniotic fluid. Fetal viral infection via the placenta can affect the formation of the auditory system and lead to congenital hearing disorders.
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