When an anorexia nervosa patient requires hospitalization for her medical condition the treatment team faces the problem of integrating the individual focus of inpatient care with the systems focus of family therapy. In this paper we propose a family-systems model of hospitalization, the aim of which is to facilitate such integration. The model draws on current theories of anorexia nervosa, as well as general concepts from psychodynamic, developmental, and family systems theories. The major hypothesis of the model is that all members of the anorexic family are developmentally arrested in the area of separation-individuation. On this assumption, we propose that the entire treatment team (including medical professionals and therapist) needs to function as "parents" to the anorexic family in much the same way that two cotherapists become parental figures in a family therapy. Specifically, the team needs to provide those parenting the responses that facilitate the family's individuation process.
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J Eat Disord
January 2025
Bodywhys - The Eating Disorders Association of Ireland, 105, Blackrock, Co. Dublin, Ireland.
Background: Current research on the transmission of trauma and eating disorders across generations is limited. However, quantitative studies suggest that the influence of parents' and grandparents' eating disorders and their prior exposure to trauma are associated with the development of eating disorders in future generations. Qualitative research exploring personal accounts of the impact of transgenerational trauma on the development of eating disorders has been largely unexplored.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
NeuroGenomics & Informatics Center, Washington University School of Medicine, St. Louis, MO, USA.
Background: Cerebrospinal fluid (CSF) is a valuable resource for the study and diagnosis of neurological diseases, but few studies have comprehensively characterized the genetic determinants of CSF protein levels that may contribute to the development of disease. These quantitative trait loci (QTL) have proven vital to identifying candidate genes for disease treatment and monitoring. Here, we utilize our largest-to-date CSF protein QTL atlas to prioritize potentially causal proteins for 14 neurological traits and examine the unique and overlapping disease mechanisms observed using CSF proteins.
View Article and Find Full Text PDFJ Eat Disord
January 2025
Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA.
Background: Avoidant/restrictive food intake disorder (ARFID) may result in significant medical sequelae. Compared to youth with eating disorders like anorexia nervosa (AN), youth with ARFID tend to be younger and are more likely to be male. We aim to describe sex differences in clinical characteristics of youth hospitalized for medical complications of ARFID and compare their characteristics with youth hospitalized for anorexia nervosa.
View Article and Find Full Text PDFEur Eat Disord Rev
January 2025
Department of Child and Adolescent Psychiatry, University of Zurich, Zurich, Switzerland.
Objective: Family-based treatment (FBT) is promising for treating adolescents with anorexia nervosa, but long-term remission rates are modest. Home treatment (HT) as a supplement to FBT aims to enhance sustainability and effectiveness by supporting recovery within the family. This study compares the cost-effectiveness of FBT alone versus FBT with additional HT for adolescents with anorexia nervosa.
View Article and Find Full Text PDFNutrients
December 2024
Orygen, Parkville, VIC 3052, Australia.
: Recent research has increasingly explored the cognitive processes underlying eating disorders (EDs), including anorexia nervosa (AN), bulimia nervosa (BN), binge eating disorder (BED), other specified feeding or eating disorders (OSFEDs), and individuals with higher weight (HW). This critical narrative review focuses on neurocognitive findings derived from mainly experimental tasks to provide a detailed understanding of cognitive functioning across these groups. Where experimental data are lacking, we draw on self-report measures and neuroimaging findings to offer supplementary insights.
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