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http://dx.doi.org/10.1093/bja/53.12.1368-aDOI Listing

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Article Synopsis
  • - The study aimed to determine if polyurethane (PU) tracheal tube cuffs help prevent ventilator-associated pneumonia (VAP) compared to polyvinyl chloride (PVC) cuffs through a comprehensive review of existing trials.
  • - Six studies with a total of 1,226 patients were analyzed, showing that PU cuffs did not significantly reduce the incidence of VAP, and the overall quality of evidence was rated as "very low."
  • - The researchers concluded that using PU cuffs does not prevent VAP and recommended further trials with better methodologies to assess their efficacy.
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K-Y™ jelly inhibits increase in endotracheal tube cuff pressure during nitrous oxide exposure in vitro.

BMC Anesthesiol

July 2018

Department of Anesthesiology, Mizonokuchi Hospital, Teikyo University School of Medicine, 5-1-1 Futako, Takatsu-ku, Kawasaki, Kanagawa, 213-8507, Japan.

Background: The increase in endotracheal tube cuff pressure due to nitrous oxide diffusion is a well-known risk during general anesthesia using nitrous oxide. We hypothesized that lubricating endotracheal tube cuffs with K-Y™ Jelly might inhibit the increase in cuff pressure that occurs during exposure to nitrous oxide.

Methods: We used two types of endotracheal tube cuffs: one made from ultrathin polyurethane (PU) and another made from conventional polyvinyl chloride (PVC).

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Article Synopsis
  • - The study assessed the effectiveness of the PneuX low-volume cuff compared to various high-volume, low-pressure (HVLP) cuffs in preventing cuff leakage, which is linked to pneumonia risk.
  • - Results showed that the PneuX cuff maintained an average tracheal wall pressure of 27.4 cm HO, comparable to HVLP cuffs, but it was the only type that consistently prevented leaks during simulations.
  • - Lubrication and PEEP both reduced leakage volumes and improved cuff performance across all tested cuffs, highlighting the role of cuff design and additional management techniques in minimizing aspiration risks.
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Background: No currently used tracheal tube offers full protection against aspiration of oropharyngeal secretions into the lower airways.

Objective: We developed a tracheal tube equipped with two polyvinylchloride (PVC) cuffs with a supplementary port opening between the cuffs through which a continuous positive pressure of 5 cmH2O is provided [double-cuffed PVC (PVCdc)]. We compared this PVCdc with four different cuff types (cylindrical PVC, conical PVC, cylindrical polyurethane and conical polyurethane).

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Background: When conventional high-volume, low-pressure cuffs of endotracheal tubes (ETTs) are inflated, channel formation due to folds in the cuff wall can occur. These channels facilitate microaspiration of subglottic secretions, which is the main pathogenic mechanism leading to intubation-related pneumonia. Ultrathin polyurethane (PU)-cuffed ETTs are developed to minimize channel formation in the cuff wall and therefore the risk of microaspiration and respiratory infections.

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