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Efficient extraction and analysis method for lead-containing nanoparticles in complex biological samples to eliminate "false" interferences by using SP-ICP-MS.

Talanta

December 2024

State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China; College of Resources and Environment, University of Chinese Academy of Sciences, Beijing, 100049, China; School of Environment, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China.

Metal-containing nanoparticles (MNPs) ubiquitously exist in the environment and organisms, playing distinct roles in the fate and toxicity of metals. However, the extraction and analysis of the MNPs in biological samples is still a great challenge and the interferences of other metal species and complex matrices remains unclear. In this work, we established a method for efficient extraction and accurate analysis of MNPs in biological samples to eliminate the interference caused by metal ions and biological matrices based on the alkali extraction and single particle mode inductively coupled plasma mass spectrometry (SP-ICP-MS).

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Per- and polyfluoroalkyl substances (PFASs), which have their origins in both industrial processes and consumer products, can be detected at all treatment stages in wastewater treatment plants (WWTPs). Quantifying the emissions of PFAS from WWTPs into the marine environment is crucial because of their potential impacts on receiving aquatic ecosystems. In this study, the levels of five PFAS were measured in both influent and effluent sewage water samples obtained from a municipal WWTP, the discharges of which flow into False Bay, on the Indian Ocean coast of Cape Town, South Africa.

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Viruses are biological entities embodied in protein-based nanoparticles devoid of metabolic activity. Hence, the colloidal, interfacial, and chemical reactivity of virus particles (VPs) profoundly affects the fate of natural and artificial viruses in biotic or abiotic aqueous systems. These rely on the physical chemistry at the outer surface of VPs.

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Kite String or Manja Cut Injury: A New Culprit.

Indian J Plast Surg

June 2024

Department of Plastic, Reconstructive, Aesthetic and Maxillofacial Surgery, Government Medical College, Nagpur, Maharashtra, India.

 Kite string injuries (manja cut injuries), particularly those caused by Chinese manja, are new culprit of emergencies especially in the month of January in Maharashtra region. These injuries commonly affect the neck, face, hands, and legs, especially among individuals traveling on two wheelers. The visibility challenge, where the kite's thread is difficult to see, further exacerbates the risk.

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Alternative splicing (AS) is emerging as an important regulatory process for complex biological processes. Transcriptomic studies therefore commonly involve the identification and quantification of alternative processing events, but the need for predicting the functional consequences of changes to the relative inclusion of alternative events remains largely unaddressed. Many tools exist for the former task, albeit each constrained to its own event type definitions.

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