The authors report a longitudinal case study of a woman with a history of bipolar affective disorder in which L-dopa shortened the manic-depressive cycle length when administered in a double-blind trial. This finding suggests a dopaminergic mechanism specifically in changing the frequency of cycling between depression and mania.
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| http://dx.doi.org/10.1176/ajp.138.12.1624 | DOI Listing |
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