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Ruthenium-106 (Ru) plaque brachytherapy as salvage treatment for retinoblastoma following intravenous chemotherapy.
Brachytherapy
January 2025
The Operation Eyesight Universal Institute for Eye Cancer, L V Prasad Eye Institute, Road no 2, Banjara Hills, Hyderabad, 500034 India.
Purpose: To describe the clinical presentation and treatment outcomes of patients undergoing Ruthenium-106 (Ru) plaque brachytherapy as salvage treatment for retinoblastoma (RB) following intravenous chemotherapy (IVC).
Methods: Retrospective chart review of 44 eyes of 42 patients. The indications for plaque brachytherapy included solid tumor recurrence (n=20; 45%), solid tumor residual (n=16; 36%), new subretinal seeds (n=5; 12%), and new solid tumor (n=3; 7%).
Indications for diagnostic whole-body iodine scan: a review of guidelines.
Nucl Med Commun
December 2024
Department of Nuclear Medicine, IRCCS Humanitas Research Hospital, Rozzano.
Objectives: Here, we have compiled all key statements derived from these guidelines and delved into details on which scenarios the diagnostic whole-body iodine scan (DxWBIS) might be useful.
Methods: We identified all relevant guidelines by searching the MEDLINE/PubMed databases, Google Scholar, and Ovid from 2006 onwards using keywords related to DxWBIS, RxWBIS, iodine scintigraphy, and iodine scan. We excluded case reports/series, original articles, and clinical trials while including guidelines or consensus opinions.
Physicians' preferencesfor radioiodine treatment of differentiated thyroid cancer in Brazil: an observational study.
Arch Endocrinol Metab
October 2024
Instituto do Câncer do Estado de São Paulo São PauloSP Brasil Instituto do Câncer do Estado de São Paulo (Icesp), São Paulo, SP, Brasil.
Objective: The aim of this observational, cross-sectional study was to investigate physicians' preferences for radioiodine (RAI) treatment in patients with differentiated thyroid cancer (DTC) in Brazil and the factors influencing RAI indications.
Materials And Methods: A survey was distributed to physicians potentially involved in DTC care in Brazil to understand the factors influencing RAI indications. The survey collected information on the profiles of the physicians, along with the characteristics of their workplaces and their preferences regarding RAI indications in three hypothetical clinical cases.
Study of transport, tissue distribution, depletion, and hepatotoxicity of Cyadox, a quinoxaline-1,4-dioxide derivative.
Front Pharmacol
September 2024
Research Center for Ecotoxicology and Food Safety, Hubei Engineering University, Xiaogan, China.
Article Synopsis
- Cyadox (CYA) is a synthetic antibacterial drug, and the study aimed to investigate its transport, distribution, and potential toxicity in animals.
- The research utilized various methods, including fluorescence and molecular docking, and found that CYA binds to bovine serum albumin (BSA) in the bloodstream, affecting the protein's structure and leading to concentration in the liver while being excreted primarily through urine and feces.
- The study concluded that CYA shows low hepatotoxicity but may influence steroid biosynthesis, providing a basis for future research on its use in food animals.
Radiosynoviorthesis with [90Y] Yttrium citrate in refractory synovitis of the knee: Experience of 2 reference hospitals.
Rev Esp Med Nucl Imagen Mol (Engl Ed)
November 2024
Unidad de Medicina Nuclear, Hospital Universitario Virgen Macarena, Sevilla, Spain.
Introduction: To describe the therapeutic efficacy of radiosynoviorthesis with [Y]Yttrium citrate (Y), in patients with chronic knee synovitis refractory to systemic treatments and/or infiltrations, correlating the results with the different etiologies and degenerative changes that they showed, in order to optimize the indication of the technique.
Material And Methods: Observational retrospective study with 32 patients (22 men and 10 women) and 34 knees, with refractory chronic knee synovitis, who underwent radiosynoviorthesis between January 2013 and December 2022. Its efficacy was described and analyzed by the subjective improvement referred by the patients and its relationship with the existing etiologies and radiological degenerative changes, expressed by the Kellgren-Lawrence (K-L) scale.
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