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A multi-omics study of the association between insomnia with objective short sleep duration phenotype and high blood pressure.
Sleep
January 2025
Department of Sleep Medicine, Mental Health Center of Shantou University, Shantou, Guangdong, People`s Republic of China.
Study Objectives: Insomnia with objective short sleep duration is associated with increased hypertension risk. We aimed to explore the mechanism underlying the association between objective short sleep duration and hypertension in patients with chronic insomnia disorder (CID) by multi-omics.
Methods: CID was defined according to International Classification of Sleep Disorders-3, and objective short sleep was based on the median value of total sleep time of the overall subjects during an overnight polysomnography.
The Bidirectional Relations Between Parental Autonomy Support, Gratitude and Academic Engagement in Chinese Adolescents.
J Youth Adolesc
January 2025
School of Psychology, Parent Education Research Center, The Intelligent Laboratory of Child and Adolescent Mental Health and Crisis Intervention of Zhejiang Province, Zhejiang Normal University, Jinhua, China.
Abundant evidence highlights the benefits of self-determined motivation (e.g., parental autonomy support as internalized extrinsic motivation, gratitude as intrinsic motivation) on academic engagement during adolescence, yet the potential mutual relations remain relatively unexplored.
View Article and Find Full Text PDFIdentification of PIF1 as a Ferroptosis-Related Prognostic Biomarker Correlated with Immune Infiltration in Hepatocellular Carcinoma.
Appl Biochem Biotechnol
January 2025
Department of General Surgery, Shanxi Provincial Cancer Hospital/Shanxi Hospital Cancer Hospital of Chinese Academy of Medical Sciences, No. 3, Gongye New Street , Xinhualing District, Taiyuan, 030001, China.
Hepatocellular carcinoma (HCC) is a primary liver malignancy characterized by high morbidity and mortality. Recently, ferroptosis has been recognized as an important factor in regulating cell growth in HCC. However, the role of ferroptosis-related genes in HCC remains unclear.
View Article and Find Full Text PDFSmart home-assisted anomaly detection system for older adults: a deep learning approach with a comprehensive set of daily activities.
Med Biol Eng Comput
January 2025
Fundación Vicomtech, Basque Research and Technology Alliance (BRTA), Mikeletegi 57, 20009, Donostia-San Sebastián, Spain.
Smart homes have the potential to enable remote monitoring of the health and well-being of older adults, leading to improved health outcomes and increased independence. However, current approaches only consider a limited set of daily activities and do not combine data from individuals. In this work, we propose the use of deep learning techniques to model behavior at the population level and detect significant deviations (i.
View Article and Find Full Text PDFTargeted metabolomics reveals novel biomarkers for gestational diabetes mellitus.
Diabetes Obes Metab
January 2025
Nanjing Women and Children's Healthcare Institute, Women's Hospital of Nanjing Medical University, Nanjing Women and Children's Healthcare Hospital, Nanjing, China.
Aims: The utilization of targeted metabolomics technology promises to facilitate the identification of novel metabolic markers in women with gestational diabetes mellitus (GDM), which may in turn facilitate a more comprehensive investigation of the underlying mechanisms of gestational diabetes GDM.
Materials And Methods: In this study, we used targeted metabolomics to identify serum metabolites from women with or without GDM. The differential metabolites were categorized and analysed using pathway analyses, correlated with maternal glucose level, and assessed as predictors of GDM by receiver operating characteristics analysis.
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