A method is described for the confirmation of chlorophenols in human urine. A hydrolyzed urine sample is analyzed by both gas chromatography (GC), and liquid chromatography (LC) with electrochemical detection and the results compared. A discussion of these results, including factors affecting separation, detection, and confirmation of chlorophenols in human urine, is included.

Download full-text PDF

Source
http://dx.doi.org/10.1093/chromsci/19.9.466DOI Listing

Publication Analysis

Top Keywords

confirmation chlorophenols
12
chlorophenols human
12
human urine
12
method confirmation
4
urine
4
urine electrochemical
4
electrochemical detector
4
detector method
4
method described
4
described confirmation
4

Similar Publications

The microbiota of cork and yellow stain as a model for a new route for the synthesis of chlorophenols and chloroanisoles from the microbial degradation of suberin and/or lignin.

Microbiome

January 2025

Instituto de Investigación de La Viña y El Vino, Escuela de Ingeniería Agraria, Universidad de León, Avenida de Portugal, 41, León, 24009, Spain.

Article Synopsis
  • Cork is primarily used for wine bottle stoppers, but it can contain 2,4,6-trichloroanisole, which causes a musty odor that negatively affects wine quality and leads to financial losses.
  • The presence of yellow stain in cork indicates a degradation linked to higher microbial populations, particularly filamentous fungi that break down lignin, and this microbiota contributes to the formation of chlorophenols and chloroanisoles.
  • Research identified specific fungal and bacterial species associated with yellow stain and demonstrated that certain strains can convert p-hydroxybenzoate into phenol, which can then be chlorinated, potentially leading to the development of 2,4,6-trichlorophenol.
View Article and Find Full Text PDF

Palladium Nanosheet Enables Synergistic Electrocatalytic Dehalogenation via Direct and Indirect Electron Transfer Mechanisms.

ACS Appl Mater Interfaces

January 2025

Key Laboratory of Environmental Biology and Pollution Control (Hunan University), Ministry of Education, College of Environmental Science and Engineering, Hunan University, Changsha 410082, China.

Electrocatalytic dehalogenation is a promising method for the remediation of chlorinated organic pollutants. The dehalogenation performance is controlled by catalytic activity, and the underlying electrocatalytic dehalogenation mechanisms need to be carefully investigated for guiding the design of catalyst. Here we report the preparation of a new Pd-based catalyst with a nanosheet structure (Pd NS) by a simple wet-chemical reduction method.

View Article and Find Full Text PDF

A series of Ag-loaded and oxygen vacancy (OV)-containing BiOBr/BiOI (Ag/BiOBr/BiOI) photocatalysts with varying Ag loading levels were synthesized via the solvothermal-photocatalytic reduction method. As confirmed via optical, photoelectrochemical, and 4-chlorophenol photodegradation experiments, a low Ag loading level significantly enhanced the photogenerated charge carrier (PCC) transfer on the BiOBr/BiOI semiconductor surface and the performance of Ag/BiOBr/BiOI photocatalysts, which was attributable to the synergism between the effect of OVs and the localized surface plasmon resonance (LSPR) of Ag nanoparticles. Additionally, BiOBr/BiOI heterojunctions facilitated efficient visible-light harvesting and PCC separation.

View Article and Find Full Text PDF

Budget impact analysis of cenobamate for epilepsy patients with drug-resistant focal onset seizures in the Netherlands.

J Med Econ

December 2025

Department of Health Services Research, Care and Public Health Research Institute (CAPHRI), Maastricht University, Maastricht, The Netherlands.

Objective: The objective of this study was to explore the financial consequences of adopting cenobamate as a treatment alternative in epilepsy patients with drug-resistant focal onset seizures (FOS) from a societal perspective in the Netherlands.

Methods: A previous budget impact model with a 5-year time horizon was adapted to the Dutch setting accounting for the eligible population, real-world market shares, treatment effectiveness and resource use in two scenarios: cenobamate with constant market share versus cenobamate with linearly increased market share up to 20%. Clinical inputs included treatment response, seizure reduction and adverse events.

View Article and Find Full Text PDF

Building hydrophobic substrate pocket to boost activity of laccase-like nanozyme through acetonitrile-mediated strategy.

J Colloid Interface Sci

February 2025

State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China; University of Science and Technology of China, Hefei, Anhui 230026, China. Electronic address:

Nanozymes, as promising alternatives to natural enzymes, offer several advantages with biocatalytic functions but remain inferior in catalytic activity. It is crucial to focus on factors that affect the enzymatic activity of nanozymes and develop strategies to make them more competitive with natural enzymes. Herein, CuVO nanorods are confirmed to own the intrinsic laccase-like activity, and an acetonitrile (MeCN)-mediated strategy is proposed for reaction acceleration by mimicking the enzymatic substrate pocket.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!