Oxyfedrine (ildamen) which stimulates beta-adrenoreceptors of smooth muscles in concentrations increasing the tissue content of cAMP produced a dose-dependent inhibition of anaphylactic bronchospasm and contractions of the guinea-pig intestine induced by administration of ovalbumin. The results obtained provide evidence in favour of oxyfedrine use for suppression of immediate type allergic reactions with the involvement of smooth muscles.
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