The activities of the enzymes of oxidative part of the pentose phosphate pathway - glucose-6-phosphate dehydrogenase (EC 1.1.1.49) and 6-phosphogluconate dehydrogenase (EC 1.1.1.44) are studied in skeletal muscles of albino rats during muscular activity of different character and in the recovery period. The most essential decrease in the activity of dehydrogenases (glucose-6-phosphate dehydrogenase-by 33 and 6-phosphogluconate dehydrogenase - by 20%) is marked under the most intensive loading -4 min swimming with a load equal 12% of the animal body weight. On the contrary, in the recovery period after the muscular activity (15 min swimming) an increase is observed in the activity of these enzymes, especially in the late periods of the recovery (3 hours after rest).
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