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Dementia Care Research and Psychosocial Factors.
Alzheimers Dement
December 2024
Unitiy Hospital, Rochester, NY, USA.
Background: Psychotropic drug prescriptions are commonly used to manage behavioral and psychological symptoms of dementia in elderly patients in long-term care facilities. The prevalence of psychotropic drug use in this population raises concerns due to potential side effects, polypharmacy and quality of life of the patients.
Aim: To assess the trends in psychotropic drug prescriptions for elderly patients with dementia following the continuous implementation of multimodal comprehensive care communication skills training for staff in a long-term care hospital.
Gut-derived lactic acid enhances tryptophan to 5-hydroxytryptamine in regulation of anxiety via .
Gut Microbes
December 2025
MOE/NHC/CAMS Key Lab of Medical Molecular Virology, School of Basic Medical Sciences, & National Clinical Research Center for Aging and Medicine, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
The gut microbiota plays a pivotal role in anxiety regulation through pathways involving neurotransmitter production, immune signaling, and metabolic interactions. Among these, gut-derived serotonin (5-hydroxytryptamine, 5-HT), synthesized from tryptophan metabolism, has been identified as a key mediator. However, it remains unclear whether specific microbial factors regulate tryptophan metabolism to influence 5-HT production and anxiety regulation.
View Article and Find Full Text PDFDementia Care Practice.
Alzheimers Dement
December 2024
University of Pittsburgh, Pittsburgh, PA, USA.
Background: Resident advocates and national nursing home dementia care initiatives have prioritized non-pharmacological approaches to manage behavioral and psychological symptoms of Alzheimer's Disease and related dementias. Evidence supports both team- and problem-based approaches to non-pharmacological dementia care, but the comparative effectiveness of these two approaches has not been examined.
Method: We implemented a cluster randomized controlled trial in 53 nursing homes ot compare the team-based and problem-based approaches to dementia care.
Dementia Care Practice.
Alzheimers Dement
December 2024
King George's Medical University, Lucknow, Uttar Pradesh, India.
Introduction: Punding is a unique stereotypical, repetitive, non-goal-directed behavior characterized by an intense fascination with daily objects. This behavior although commonly seen in dementia patients is relatively less studied. In this study, we aimed to assess the effectiveness of combination treatment of escitalopram and risperidone treatment in the punding behavior of dementia patients.
View Article and Find Full Text PDFThe Impact of Silver Codoping on Tb Luminescence in Lithium Tetraborate Glasses.
Luminescence
January 2025
Vlokh Institute of Physical Optics, Ivan Franko National University of Lviv, Lviv, Ukraine.
Spectroscopic properties of Tb-doped and Tb-Ag codoped lithium tetraborate (LTB) glasses with LiBO (or LiO-2BO) composition are investigated and analysed using electron paramagnetic resonance (EPR), optical absorption, photoluminescence (PL) and photoluminescence excitation (PLE) spectra, PL decay kinetics and absolute quantum yield (QY) measurements. PL spectra of the investigated glasses show numerous narrow emission bands corresponding to the D → F (J = 6-0) and D → F (J = 5-3) transitions of Tb (4f) ions. The most intense PL band of Tb ions at 541 nm (D → F transition) is characterised by a lifetime slightly exceeding 2.
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