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Performance of a new quantitative computed tomography index for interstitial lung disease assessment in systemic sclerosis.
Sci Rep
July 2019
Rheumatology Unit, Department of Precision Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.
Quantitative high resolution computed tomography (HRCT) may objectively assess systemic sclerosis (SSc)-interstitial lung disease (ILD) extent, using three basic densitometric measures: mean lung attenuation (MLA), skewness, and kurtosis. This prospective study aimed to develop a composite index - computerized integrated index (CII) - that accounted for MLA, skewness, and kurtosis by means of Principal Component Analysis over HRCTs of 83 consecutive SSc subjects, thus eliminating redundancies. Correlations among CII, cardiopulmonary function and immune-inflammatory biomarkers (e.
View Article and Find Full Text PDFPulmonary quantitative CT imaging in focal and diffuse disease: current research and clinical applications.
Br J Radiol
February 2018
1 Department of Medicine and Surgery (DiMeC), Section of Radiology, Unit of Surgical Sciences, University of Parma, Parma , Italy.
The frenetic development of imaging technology-both hardware and software-provides exceptional potential for investigation of the lung. In the last two decades, CT was exploited for detailed characterization of pulmonary structures and description of respiratory disease. The introduction of volumetric acquisition allowed increasingly sophisticated analysis of CT data by means of computerized algorithm, namely quantitative CT (QCT).
View Article and Find Full Text PDFRole of Densitometric Criteria in Evaluation of Effectiveness of Antiangiogenic Therapies in Metastatic Colorectal Cancer: An Italian Clinical Experience.
Anticancer Res
September 2017
Department of Radiology, University of Palermo, Palermo, Italy.
Background/aim: To evaluate the role of densitometric criterion using the Choi Criteria in the assessment of the response to antiangiogenic treatments of metastatic colorectal cancer (mCRC) compared to the RECIST criteria.
Patients And Methods: Fifty-four patients (mean age=50.6 years) affected by advanced colorectal cancer and with hepatic and possibly peritoneal and pulmonary metastases, that can be treated with bevacizumab, were prospectively evaluated by computerized tomography (CT) scan.
Comparative evaluation of bovine derived hydroxyapatite and synthetic hydroxyapatite graft in bone regeneration of human maxillary cystic defects: a clinico-radiological study.
Indian J Dent Res
December 2016
Department of Oral and Maxillofacial Surgery, SIBAR Institute of Dental Sciences, Guntur, Andhra Pradesh, India.
Introduction: Bone grafts are frequently used in the treatment of bone defects. Bone harvesting can cause postoperative complications and sometimes does not provide a sufficient quantity of bone. Therefore, synthetic biomaterials have been investigated as an alternative to autogenous bone grafts.
View Article and Find Full Text PDFDe novo bone regeneration in human extraction sites using recombinant human bone morphogenetic protein-2/ACS: a clinical, histomorphometric, densitometric, and 3-dimensional cone-beam computerized tomographic scan evaluation.
Implant Dent
April 2014
*Private Practice, Periodontics, Wilmington, NC. †Private Practice, Oral Maxillofacial Surgery, Palm Harbor, FL; Director, Pikos Implant Institute, Spring Hill, FL. ‡Senior Research Scientist, Hard Tissue Research Laboratory, University of Minnesota School of Dentistry, Minneapolis, MN.
Introduction: To preserve alveolar bone after extractions, it is important to graft socket sites to prevent bone loss from repair and remodeling.
Objective: The objective of this case series was to assess the clinical, densitometric, and histomorphometric results from extraction sockets treated with recombinant human bone morphogenetic protein (rhBMP-2/ACS).
Study Design: After extraction and socket debridement, INFUSE (rhBMP-2) on absorbable sponges was placed over each socket.
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