The paper describes the results of study of 71 patients with chronic diseases of the lungs. The methods of investigation were directed at eliciting changes in extravascular, vascular and intravascular factors of the microcirculatory system. Considerable disorders of the microcirculation have been found in respiratory insufficiency and their dependence of the stage of insufficiency. Comparison of the degree of microcirculatory shifts with the gaseous composition of the blood and the acid-base balance has been made. The stages of microcirculatory changes run parallel to the severity of respiratory insufficiency, and the causes leading to pathology of microcirculation in respiratory insufficiency are multifactorial in character, the main being changes in the gaseous composition of the blood.

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