AI Article Synopsis
- 99mTc-human albumin microspheres were injected into the hepatic arteries of 24 liver cancer patients before chemotherapy to study blood flow and distribution.
- The results showed that the distribution of the microspheres differed from traditional imaging in most patients, indicating varied blood flow patterns.
- The study revealed that most patients had significant liver uptake of the microspheres, and about half displayed increased arterial blood supply to tumor regions, aiding in evaluating liver perfusion.
Article Abstract
99mTc-human albumin microspheres were injected at a slow rate into the hepatic arteries of 24 patients before starting intraarterial chemotherapy for liver cancer. The distribution patterns of radiolabeled microspheres were significantly different from those obtained in contrast angiography in 13 of 22 patients. Liver uptake of slowly injected microspheres was greater than 75% in 16 of 24 patients and less than 25% in 4 of 24 patients. A significantly increased arterial blood supply to intrahepatic neoplastic regions was demonstrated in 12 of 20 patients. Microsphere examination allowed an easy evaluation of the relative perfusion of the liver and of the intrahepatic distribution of arterial blood flow in all patients.
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| http://dx.doi.org/10.1007/BF00252806 | DOI Listing |
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